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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24B
All Species:
6.36
Human Site:
S421
Identified Species:
10.77
UniProt:
O95487
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95487
NP_001036199.1
1268
137418
S421
Y
P
D
M
L
S
S
S
A
S
S
P
A
P
D
Chimpanzee
Pan troglodytes
XP_001136519
1173
128734
E356
S
D
D
E
E
E
E
E
E
D
E
E
A
G
V
Rhesus Macaque
Macaca mulatta
XP_001087955
1263
137118
S418
D
M
L
S
S
S
A
S
S
P
A
P
D
P
A
Dog
Lupus familis
XP_545021
1258
136639
P411
A
L
E
G
G
S
Y
P
D
M
L
S
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
Q274
G
G
F
L
A
T
P
Q
L
V
N
Q
N
P
K
Rat
Rattus norvegicus
NP_001099944
1242
134697
A406
P
D
M
H
S
S
S
A
S
S
P
V
P
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506149
1278
138146
Y421
Y
P
T
L
Q
P
G
Y
Q
N
A
A
P
L
S
Chicken
Gallus gallus
NP_001026306
1234
134555
T407
Y
P
E
T
R
S
V
T
N
S
P
V
P
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340708
1097
118527
Q281
Q
P
G
Y
S
T
A
Q
G
Y
T
P
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394884
843
95632
Q27
Y
S
E
S
Y
S
D
Q
M
N
H
I
N
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784354
1353
146633
S458
V
S
F
S
A
V
E
S
G
Y
L
S
V
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFU0
1038
113942
F222
V
L
Q
A
P
T
P
F
Q
T
S
Q
G
P
P
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
Q110
V
Q
M
G
T
P
L
Q
Q
Q
Q
Q
P
M
A
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
S134
Q
A
P
D
P
Y
Y
S
Q
G
V
P
P
A
A
Conservation
Percent
Protein Identity:
100
86.2
97.7
92.6
N.A.
54.3
81.7
N.A.
71
74.2
N.A.
51.4
N.A.
N.A.
39.9
N.A.
39.8
Protein Similarity:
100
87.5
98.8
95.5
N.A.
66.6
87.4
N.A.
78.7
81.2
N.A.
63.6
N.A.
N.A.
52.1
N.A.
54.4
P-Site Identity:
100
13.3
26.6
6.6
N.A.
6.6
20
N.A.
13.3
26.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
13.3
46.6
20
N.A.
26.6
33.3
N.A.
33.3
40
N.A.
33.3
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
28
30.6
Protein Similarity:
N.A.
N.A.
N.A.
48.4
43
43.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
15
0
15
8
8
0
15
8
15
8
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
15
15
8
0
0
8
0
8
8
0
0
8
8
8
% D
% Glu:
0
0
22
8
8
8
15
8
8
0
8
8
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
15
8
0
8
0
15
8
0
0
8
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
15
8
15
8
0
8
0
8
0
15
0
0
8
0
% L
% Met:
0
8
15
8
0
0
0
0
8
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
15
8
0
15
8
0
% N
% Pro:
8
29
8
0
15
15
15
8
0
8
15
29
43
29
15
% P
% Gln:
15
8
8
0
8
0
0
29
29
8
8
22
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
15
0
22
22
43
15
29
15
22
15
15
8
8
8
% S
% Thr:
0
0
8
8
8
22
0
8
0
8
8
0
0
8
0
% T
% Val:
22
0
0
0
0
8
8
0
0
8
8
15
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
29
0
0
8
8
8
15
8
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _