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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 5.76
Human Site: S516 Identified Species: 9.74
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 S516 G G L S L Q S S P Q P E S L R
Chimpanzee Pan troglodytes XP_001136519 1173 128734 I451 Q N A T A P L I S G V Q P S N
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 Q513 L S L Q S S P Q P E S L R P V
Dog Lupus familis XP_545021 1258 136639 S506 G G L S L Q S S P Q P E S L R
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L369 L Q P P V P N L L E D I Q K L
Rat Rattus norvegicus NP_001099944 1242 134697 L501 E S L R P V N L T Q E K N I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 T516 D S F R C T L T N I P Q T Q A
Chicken Gallus gallus NP_001026306 1234 134555 V502 Q D R N I L P V S S V P A P V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 P376 T P P L P C L P Q D L Q R M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 I122 E K V E S P K I K L H Q E F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 P553 S H L S G A P P S A G D F A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 H317 E M Y P M N C H S R Y L R L T
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 L205 K S K L P F G L V I R P Y Q H
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 L229 P K Y V R S T L N A V P T T H
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 0 13.3 100 N.A. 0 13.3 N.A. 6.6 0 N.A. 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 13.3 20 100 N.A. 20 40 N.A. 26.6 20 N.A. 13.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 0
P-Site Similarity: N.A. N.A. N.A. 20 0 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 0 0 0 15 0 0 8 8 8 % A
% Cys: 0 0 0 0 8 8 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 8 8 8 0 0 0 % D
% Glu: 22 0 0 8 0 0 0 0 0 15 8 15 8 0 0 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 0 8 8 0 % F
% Gly: 15 15 0 0 8 0 8 0 0 8 8 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 15 % H
% Ile: 0 0 0 0 8 0 0 15 0 15 0 8 0 8 0 % I
% Lys: 8 15 8 0 0 0 8 0 8 0 0 8 0 8 0 % K
% Leu: 15 0 36 15 15 8 22 29 8 8 8 15 0 22 22 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 8 0 8 15 0 15 0 0 0 8 0 15 % N
% Pro: 8 8 15 15 22 22 22 15 22 0 22 22 8 15 8 % P
% Gln: 15 8 0 8 0 15 0 8 8 22 0 29 8 15 0 % Q
% Arg: 0 0 8 15 8 0 0 0 0 8 8 0 22 0 15 % R
% Ser: 8 29 0 22 15 15 15 15 29 8 8 0 15 8 0 % S
% Thr: 8 0 0 8 0 8 8 8 8 0 0 0 15 8 8 % T
% Val: 0 0 8 8 8 8 0 8 8 0 22 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _