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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 17.27
Human Site: T1197 Identified Species: 29.23
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 T1197 A S I P Q K M T H L P E L D T
Chimpanzee Pan troglodytes XP_001136519 1173 128734 H1107 L T D E G A V H V N D R V V P
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 T1192 A S I P Q K M T H L P E L D T
Dog Lupus familis XP_545021 1258 136639 T1187 A S I P Q K M T H L P E L D T
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L1024 T M T D L P E L D T P E S A R
Rat Rattus norvegicus NP_001099944 1242 134697 T1171 G S I P Q K M T H L P E L D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 P1212 Y P V T A S P P G L V R A Q R
Chicken Gallus gallus NP_001026306 1234 134555 T1163 A S I P Q R M T Q L P E I D A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 L1031 N M T Q L P E L D T A E S C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 E777 E E F Y E L P E I E T T E S E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 L1254 L G D A R D A L V N V C L D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 M972 F Q E Q E N G M S K K L M R L
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 R860 R N I I N Q L R N H D D V I T
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 V884 D N D F N E R V R N V I A K S
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 0 100 100 N.A. 13.3 93.3 N.A. 6.6 73.3 N.A. 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. 13.3 93.3 N.A. 13.3 86.6 N.A. 6.6 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 8 8 8 8 0 0 0 8 0 15 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % C
% Asp: 8 0 22 8 0 8 0 0 15 0 15 8 0 43 0 % D
% Glu: 8 8 8 8 15 8 15 8 0 8 0 50 8 0 8 % E
% Phe: 8 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 8 0 8 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 29 8 0 0 0 0 0 % H
% Ile: 0 0 43 8 0 0 0 0 8 0 0 8 8 8 0 % I
% Lys: 0 0 0 0 0 29 0 0 0 8 8 0 0 8 0 % K
% Leu: 15 0 0 0 15 8 8 22 0 43 0 8 36 0 8 % L
% Met: 0 15 0 0 0 0 36 8 0 0 0 0 8 0 0 % M
% Asn: 8 15 0 0 15 8 0 0 8 22 0 0 0 0 0 % N
% Pro: 0 8 0 36 0 15 15 8 0 0 43 0 0 0 8 % P
% Gln: 0 8 0 15 36 8 0 0 8 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 8 8 8 8 8 0 0 15 0 8 22 % R
% Ser: 0 36 0 0 0 8 0 0 8 0 0 0 15 8 15 % S
% Thr: 8 8 15 8 0 0 0 36 0 15 8 8 0 0 36 % T
% Val: 0 0 8 0 0 0 8 8 15 0 22 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _