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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 4.24
Human Site: T316 Identified Species: 7.18
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 T316 K S S P V V S T V L S G S S G
Chimpanzee Pan troglodytes XP_001136519 1173 128734 Q251 S P G L P S T Q D N L I R N H
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 T314 K S S P V V S T V L S G S S S
Dog Lupus familis XP_545021 1258 136639 P307 P V M Q N V Q P L K S S P V V
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 H170 N P N L T A D H Q Y V S S G D
Rat Rattus norvegicus NP_001099944 1242 134697 A302 P K P S S V V A T V L P G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 G304 Q E G M Q Y G G Y I N N Q A S
Chicken Gallus gallus NP_001026306 1234 134555 A302 L T K P G F G A P A S S A L I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 A177 I A P P P F A A A P P P S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 K317 K L H P D Y Q K I Q V S P D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 F118 Q R F P S P P F P T T Q N P P
Baker's Yeast Sacchar. cerevisiae P40482 926 103617
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 Q30 Q Y P V E P A Q Q A Y G S P A
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 0 93.3 13.3 N.A. 6.6 6.6 N.A. 0 13.3 N.A. 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 13.3 93.3 20 N.A. 13.3 13.3 N.A. 26.6 26.6 N.A. 33.3 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 0 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 15 22 8 15 0 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 8 0 0 0 0 8 8 % D
% Glu: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 15 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 8 0 15 8 0 0 0 22 8 8 8 % G
% His: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 0 8 8 0 8 0 0 15 % I
% Lys: 22 8 8 0 0 0 0 8 0 8 0 0 0 0 0 % K
% Leu: 8 8 0 15 0 0 0 0 8 15 15 0 0 8 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 8 0 0 0 0 8 8 8 8 8 0 % N
% Pro: 15 15 22 43 15 15 8 8 15 8 8 15 15 22 8 % P
% Gln: 22 0 0 8 8 0 15 15 15 8 0 8 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 8 15 15 8 15 8 15 0 0 0 29 29 36 15 22 % S
% Thr: 0 8 0 0 8 0 8 15 8 8 8 0 0 8 0 % T
% Val: 0 8 0 8 15 29 8 0 15 8 15 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 15 0 0 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _