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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 6.67
Human Site: Y406 Identified Species: 11.28
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 Y406 A S P M P N S Y D A L E G G S
Chimpanzee Pan troglodytes XP_001136519 1173 128734 A341 V N N Q A S S A P T P L S S T
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 A403 P M P N S Y D A L E G G S Y P
Dog Lupus familis XP_545021 1258 136639 S396 S S T T S S A S P M P N S Y D
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 N259 N G S T A A H N T Y D E I E G
Rat Rattus norvegicus NP_001099944 1242 134697 D391 S P L P N S Y D A L E G G S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 T406 S T P Q P A K T S K P F G Y G
Chicken Gallus gallus NP_001026306 1234 134555 Y392 A S P V L N N Y D A L E G G G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 V266 L G Q M S R P V G S G Y P S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 P12 L S N P M S M P P D S M N K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 A443 M L R P P Q P A V Y L F L L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 F207 V G G S Q P S F P G Y P S K Q
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 A95 V P L V D P N A Y M Q P Q V P
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 A119 P Y G A P Q P A V P G V G G Y
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. 20 73.3 N.A. 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 6.6 26.6 N.A. 6.6 20 N.A. 33.3 86.6 N.A. 13.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 20
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 8 15 15 8 36 8 15 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 8 15 8 8 0 0 0 15 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 8 22 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 15 0 0 0 % F
% Gly: 0 22 15 0 0 0 0 0 8 8 22 15 36 22 22 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 0 15 0 % K
% Leu: 15 8 15 0 8 0 0 0 8 8 22 8 8 8 8 % L
% Met: 8 8 0 15 8 0 8 0 0 15 0 8 0 0 0 % M
% Asn: 8 8 15 8 8 15 15 8 0 0 0 8 8 0 0 % N
% Pro: 15 15 29 22 29 15 22 8 29 8 22 15 8 0 15 % P
% Gln: 0 0 8 15 8 15 0 0 0 0 8 0 8 0 8 % Q
% Arg: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 8 % R
% Ser: 22 29 8 8 22 29 22 8 8 8 8 0 29 22 8 % S
% Thr: 0 8 8 15 0 0 0 8 8 8 0 0 0 0 8 % T
% Val: 22 0 0 15 0 0 0 8 15 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 8 15 8 15 8 8 0 22 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _