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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN14
All Species:
19.39
Human Site:
T226
Identified Species:
47.41
UniProt:
O95500
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95500
NP_001139549.1
239
25699
T226
D
N
R
A
P
S
V
T
S
A
T
H
S
G
Y
Chimpanzee
Pan troglodytes
XP_521208
197
20893
C185
G
I
I
L
C
F
S
C
S
S
Q
R
N
R
S
Rhesus Macaque
Macaca mulatta
XP_001084289
239
25658
T226
D
N
R
A
P
S
V
T
S
A
T
H
S
G
Y
Dog
Lupus familis
XP_544876
237
25129
T224
D
N
R
A
P
S
A
T
S
A
S
L
S
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S3
239
25596
T226
D
N
R
A
P
S
V
T
S
A
A
H
S
G
Y
Rat
Rattus norvegicus
P56745
211
22824
Y199
S
Y
P
T
P
R
P
Y
P
K
P
T
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512437
235
24858
S223
N
Y
A
P
S
L
T
S
A
S
R
S
S
Y
R
Chicken
Gallus gallus
XP_425552
235
24875
S223
N
H
A
S
S
L
T
S
A
S
H
S
G
Y
R
Frog
Xenopus laevis
NP_001086045
236
25557
S223
S
N
H
V
P
S
W
S
S
A
S
H
H
G
Y
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
K196
E
G
R
A
Y
S
V
K
Y
S
A
P
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.9
98.3
89.5
N.A.
93.3
42.2
N.A.
74.9
69.4
59.4
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.6
98.7
93.7
N.A.
95.8
59.4
N.A.
84
82
75.7
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
80
N.A.
93.3
6.6
N.A.
6.6
0
53.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
93.3
6.6
N.A.
33.3
40
66.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
50
0
0
10
0
20
50
20
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
10
50
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
10
40
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
20
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
50
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
10
60
0
10
0
10
0
10
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
50
0
0
10
0
0
0
0
10
10
10
10
20
% R
% Ser:
20
0
0
10
20
60
10
30
60
40
20
20
50
20
20
% S
% Thr:
0
0
0
10
0
0
20
40
0
0
20
10
0
0
0
% T
% Val:
0
0
0
10
0
0
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
10
0
0
10
10
0
0
0
0
20
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _