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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN14
All Species:
8.48
Human Site:
Y194
Identified Species:
20.74
UniProt:
O95500
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95500
NP_001139549.1
239
25699
Y194
D
E
A
P
Y
R
P
Y
Q
A
P
P
R
A
T
Chimpanzee
Pan troglodytes
XP_521208
197
20893
P153
D
F
Y
S
P
L
V
P
D
S
M
K
F
E
I
Rhesus Macaque
Macaca mulatta
XP_001084289
239
25658
Y194
D
E
A
P
Y
R
P
Y
Q
A
P
P
R
A
T
Dog
Lupus familis
XP_544876
237
25129
G192
C
L
D
E
V
P
S
G
P
H
Q
V
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S3
239
25596
Y194
D
E
A
P
Y
R
P
Y
P
P
Q
S
R
A
G
Rat
Rattus norvegicus
P56745
211
22824
T167
E
F
G
Q
A
L
F
T
G
W
A
A
A
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512437
235
24858
R191
S
C
Q
R
E
A
P
R
V
P
Y
Q
L
P
P
Chicken
Gallus gallus
XP_425552
235
24875
Q191
S
G
Q
C
G
T
D
Q
G
P
R
Q
P
R
P
Frog
Xenopus laevis
NP_001086045
236
25557
T191
T
S
C
Q
K
D
S
T
P
L
P
Y
T
P
Q
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
L164
K
R
E
L
G
A
S
L
F
I
G
W
C
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.9
98.3
89.5
N.A.
93.3
42.2
N.A.
74.9
69.4
59.4
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.6
98.7
93.7
N.A.
95.8
59.4
N.A.
84
82
75.7
57.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
0
N.A.
66.6
0
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
0
N.A.
66.6
13.3
N.A.
6.6
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
10
20
0
0
0
20
10
10
10
40
0
% A
% Cys:
10
10
10
10
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
40
0
10
0
0
10
10
0
10
0
0
0
0
0
0
% D
% Glu:
10
30
10
10
10
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
20
0
0
0
0
10
0
10
0
0
0
10
0
0
% F
% Gly:
0
10
10
0
20
0
0
10
20
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
10
0
20
0
10
0
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
30
10
10
40
10
30
30
30
20
20
30
20
% P
% Gln:
0
0
20
20
0
0
0
10
20
0
20
20
0
0
10
% Q
% Arg:
0
10
0
10
0
30
0
10
0
0
10
0
30
10
10
% R
% Ser:
20
10
0
10
0
0
30
0
0
10
0
10
0
10
10
% S
% Thr:
10
0
0
0
0
10
0
20
0
0
0
0
10
0
20
% T
% Val:
0
0
0
0
10
0
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% W
% Tyr:
0
0
10
0
30
0
0
30
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _