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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAMEF1
All Species:
3.94
Human Site:
S405
Identified Species:
17.33
UniProt:
O95521
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95521
NP_075389.1
474
55162
S405
L
R
H
T
S
G
L
S
K
L
S
L
E
T
Y
Chimpanzee
Pan troglodytes
B3Y613
784
89806
K457
S
V
T
G
C
I
P
K
T
L
E
I
L
D
V
Rhesus Macaque
Macaca mulatta
XP_001106795
480
55394
S406
L
R
H
T
G
R
L
S
K
L
S
L
E
T
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
A421
L
R
D
S
V
V
Q
A
E
L
R
T
V
V
H
Rat
Rattus norvegicus
Q569B5
493
54896
A421
L
R
D
S
V
I
Q
A
E
L
R
T
V
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
P437
L
Q
N
L
V
R
L
P
E
L
H
L
V
V
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
60.8
N.A.
N.A.
24.5
24.9
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
34.5
72.7
N.A.
N.A.
42.3
43.6
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
86.6
N.A.
N.A.
46.6
46.6
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
0
0
0
0
0
0
0
17
0
% D
% Glu:
0
0
0
0
0
0
0
0
50
0
17
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
17
17
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
34
0
0
0
0
0
0
0
17
0
0
0
34
% H
% Ile:
0
0
0
0
0
34
0
0
0
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
34
0
0
0
0
0
0
% K
% Leu:
84
0
0
17
0
0
50
0
0
100
0
50
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
17
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
34
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
0
0
0
34
0
0
0
0
34
0
0
0
0
% R
% Ser:
17
0
0
34
17
0
0
34
0
0
34
0
0
0
0
% S
% Thr:
0
0
17
34
0
0
0
0
17
0
0
34
0
34
0
% T
% Val:
0
17
0
0
50
17
0
0
0
0
0
0
50
50
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _