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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADK
All Species:
13.33
Human Site:
S117
Identified Species:
22.56
UniProt:
O95544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95544
NP_075394.3
446
49228
S117
I
K
K
M
R
D
A
S
L
L
Q
P
F
K
E
Chimpanzee
Pan troglodytes
XP_001147420
439
48074
S117
I
K
K
M
R
D
A
S
L
L
Q
P
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001097354
724
78796
L118
K
K
M
R
D
A
S
L
L
Q
P
F
K
E
L
Dog
Lupus familis
XP_848833
454
50061
L118
K
K
M
R
D
A
S
L
L
Q
P
F
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P58058
439
48607
L118
K
K
I
R
D
A
S
L
L
Q
P
F
K
E
L
Rat
Rattus norvegicus
NP_001103148
444
49218
S117
I
K
K
I
R
D
A
S
L
L
Q
P
F
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508266
441
48900
L116
K
I
R
D
A
S
L
L
Q
P
F
K
E
L
C
Chicken
Gallus gallus
NP_001026041
446
49549
L116
K
K
I
R
D
A
S
L
L
Q
P
F
K
E
L
Frog
Xenopus laevis
NP_001080015
445
49838
S117
I
K
K
V
R
D
D
S
L
L
K
P
F
K
E
Zebra Danio
Brachydanio rerio
NP_001017580
438
48460
G117
I
K
K
I
R
D
A
G
L
L
Q
P
F
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097302
450
49903
N129
D
W
L
L
Q
E
K
N
M
V
V
W
V
E
S
Honey Bee
Apis mellifera
XP_392018
433
48473
Q117
S
V
L
P
P
F
V
Q
L
V
T
W
L
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5W3
985
109169
I297
I
E
N
G
F
K
T
I
V
D
L
R
A
E
I
Baker's Yeast
Sacchar. cerevisiae
P32622
495
55855
R125
I
S
T
V
F
L
M
R
E
V
V
E
W
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
61.3
90.7
N.A.
91
91.6
N.A.
86.3
84.9
80.9
72.4
N.A.
55.5
56
N.A.
N.A.
Protein Similarity:
100
95.5
61.4
93.6
N.A.
94.6
95.7
N.A.
91.4
90.3
88.5
80.9
N.A.
70.4
73.3
N.A.
N.A.
P-Site Identity:
100
100
13.3
13.3
N.A.
13.3
93.3
N.A.
0
13.3
80
86.6
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
26.6
100
N.A.
6.6
26.6
93.3
93.3
N.A.
46.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.7
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
29
29
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
8
29
36
8
0
0
8
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
8
0
0
8
8
43
43
% E
% Phe:
0
0
0
0
15
8
0
0
0
0
8
29
36
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
8
15
15
0
0
0
8
0
0
0
0
0
15
8
% I
% Lys:
36
65
36
0
0
8
8
0
0
0
8
8
29
36
0
% K
% Leu:
0
0
15
8
0
8
8
36
72
36
8
0
8
8
36
% L
% Met:
0
0
15
15
0
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
8
0
0
0
0
8
29
36
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
8
29
29
0
0
0
0
% Q
% Arg:
0
0
8
29
36
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
8
8
0
0
0
8
29
29
0
0
0
0
0
0
8
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
0
8
0
15
0
0
8
0
8
22
15
0
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
15
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _