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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADK
All Species:
28.79
Human Site:
S222
Identified Species:
48.72
UniProt:
O95544
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95544
NP_075394.3
446
49228
S222
F
S
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
Chimpanzee
Pan troglodytes
XP_001147420
439
48074
S222
F
S
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
Rhesus Macaque
Macaca mulatta
XP_001097354
724
78796
S223
F
S
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
Dog
Lupus familis
XP_848833
454
50061
S223
F
N
F
E
N
F
Q
S
Q
V
T
Q
V
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
P58058
439
48607
S223
F
N
F
E
N
F
Q
S
Q
V
N
Q
V
I
E
Rat
Rattus norvegicus
NP_001103148
444
49218
Q222
P
F
N
F
E
N
F
Q
S
Q
V
N
Q
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508266
441
48900
Q221
N
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
G
Chicken
Gallus gallus
NP_001026041
446
49549
S221
F
N
F
E
N
F
Q
S
Q
V
T
Q
V
I
E
Frog
Xenopus laevis
NP_001080015
445
49838
Q222
P
F
N
F
D
N
F
Q
T
Q
V
T
Q
V
I
Zebra Danio
Brachydanio rerio
NP_001017580
438
48460
S222
F
N
F
D
T
Y
Q
S
Q
V
T
E
V
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097302
450
49903
S234
H
A
A
L
T
L
R
S
R
L
R
C
V
M
H
Honey Bee
Apis mellifera
XP_392018
433
48473
L222
Q
E
Q
V
T
N
V
L
E
G
H
A
A
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5W3
985
109169
L402
R
E
V
S
E
T
K
L
G
S
N
A
V
V
S
Baker's Yeast
Sacchar. cerevisiae
P32622
495
55855
E230
F
E
F
Q
N
F
K
E
T
L
K
H
I
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
61.3
90.7
N.A.
91
91.6
N.A.
86.3
84.9
80.9
72.4
N.A.
55.5
56
N.A.
N.A.
Protein Similarity:
100
95.5
61.4
93.6
N.A.
94.6
95.7
N.A.
91.4
90.3
88.5
80.9
N.A.
70.4
73.3
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
0
93.3
0
66.6
N.A.
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
6.6
100
13.3
93.3
N.A.
46.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.7
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
0
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
22
8
43
15
0
0
8
8
0
0
8
0
8
43
% E
% Phe:
58
22
58
15
8
50
15
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
15
50
15
% I
% Lys:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
8
0
15
0
15
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
29
15
8
50
22
0
0
0
0
15
8
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
8
50
22
50
15
8
43
15
0
8
% Q
% Arg:
8
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% R
% Ser:
0
22
0
8
0
0
8
58
8
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
22
8
0
0
15
8
43
8
0
0
15
% T
% Val:
0
0
8
8
0
0
8
0
8
50
15
8
65
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _