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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADK
All Species:
30.61
Human Site:
S395
Identified Species:
51.79
UniProt:
O95544
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95544
NP_075394.3
446
49228
S395
Q
E
I
R
H
G
D
S
I
S
I
T
T
S
C
Chimpanzee
Pan troglodytes
XP_001147420
439
48074
P407
P
S
I
C
V
R
D
P
V
S
D
W
F
E
S
Rhesus Macaque
Macaca mulatta
XP_001097354
724
78796
S396
Q
E
I
R
H
G
D
S
I
S
I
T
T
S
C
Dog
Lupus familis
XP_848833
454
50061
S396
Q
E
I
R
H
G
D
S
I
S
I
T
T
S
C
Cat
Felis silvestris
Mouse
Mus musculus
P58058
439
48607
S393
I
R
H
G
D
S
I
S
I
T
T
S
C
Y
P
Rat
Rattus norvegicus
NP_001103148
444
49218
S393
I
R
H
G
D
S
I
S
I
T
T
S
C
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508266
441
48900
S393
Q
E
I
S
Y
G
D
S
I
S
I
T
T
S
C
Chicken
Gallus gallus
NP_001026041
446
49549
S393
Q
E
I
C
H
G
D
S
I
S
I
T
T
S
C
Frog
Xenopus laevis
NP_001080015
445
49838
S394
Q
E
I
C
H
G
D
S
I
S
I
T
T
S
C
Zebra Danio
Brachydanio rerio
NP_001017580
438
48460
T392
I
A
C
G
D
S
I
T
I
T
T
S
C
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097302
450
49903
V417
A
D
G
L
H
W
N
V
R
K
R
Q
K
C
L
Honey Bee
Apis mellifera
XP_392018
433
48473
S395
Q
I
T
D
W
F
D
S
L
A
E
C
L
H
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5W3
985
109169
S944
Q
Q
L
S
R
G
D
S
V
R
I
Y
M
S
Q
Baker's Yeast
Sacchar. cerevisiae
P32622
495
55855
S436
K
P
F
A
H
I
L
S
P
K
N
Q
E
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
61.3
90.7
N.A.
91
91.6
N.A.
86.3
84.9
80.9
72.4
N.A.
55.5
56
N.A.
N.A.
Protein Similarity:
100
95.5
61.4
93.6
N.A.
94.6
95.7
N.A.
91.4
90.3
88.5
80.9
N.A.
70.4
73.3
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
13.3
13.3
N.A.
86.6
93.3
93.3
6.6
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
26.6
26.6
N.A.
93.3
93.3
93.3
26.6
N.A.
20
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.7
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
8
22
0
0
0
0
0
0
0
8
22
8
43
% C
% Asp:
0
8
0
8
22
0
65
0
0
0
8
0
0
0
0
% D
% Glu:
0
43
0
0
0
0
0
0
0
0
8
0
8
8
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
22
0
50
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
50
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
22
8
50
0
0
8
22
0
65
0
50
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
15
0
0
8
8
0
% K
% Leu:
0
0
8
8
0
0
8
0
8
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
8
8
0
0
0
0
0
22
% P
% Gln:
58
8
0
0
0
0
0
0
0
0
0
15
0
0
8
% Q
% Arg:
0
15
0
22
8
8
0
0
8
8
8
0
0
0
0
% R
% Ser:
0
8
0
15
0
22
0
79
0
50
0
22
0
50
8
% S
% Thr:
0
0
8
0
0
0
0
8
0
22
22
43
43
0
0
% T
% Val:
0
0
0
0
8
0
0
8
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
8
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _