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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NADK All Species: 15.15
Human Site: S48 Identified Species: 25.64
UniProt: O95544 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95544 NP_075394.3 446 49228 S48 R A K S R S L S A S P A L G S
Chimpanzee Pan troglodytes XP_001147420 439 48074 S48 R A K S R S L S A S P A L G S
Rhesus Macaque Macaca mulatta XP_001097354 724 78796 A49 A K S R S L S A S P A L G S T
Dog Lupus familis XP_848833 454 50061 A49 A K S R S L S A S P A L A S A
Cat Felis silvestris
Mouse Mus musculus P58058 439 48607 A49 A K S R S L S A S P A L G S T
Rat Rattus norvegicus NP_001103148 444 49218 S48 R A K S R S L S A S P A L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508266 441 48900 S47 K S R S L S A S P A L G S T K
Chicken Gallus gallus NP_001026041 446 49549 A47 A K S R S L S A S P A L G S T
Frog Xenopus laevis NP_001080015 445 49838 S48 R T K S R S L S V S P A P G S
Zebra Danio Brachydanio rerio NP_001017580 438 48460 M48 N R T K A R S M S M P S A Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097302 450 49903 L60 Q F R R T R S L N A P S P V Q
Honey Bee Apis mellifera XP_392018 433 48473 A48 L T V D Y T E A L E P R R R T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5W3 985 109169 Q228 G I V W R K L Q K L K N V C Y
Baker's Yeast Sacchar. cerevisiae P32622 495 55855 Y56 P G L M R C G Y H D A K N W V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 61.3 90.7 N.A. 91 91.6 N.A. 86.3 84.9 80.9 72.4 N.A. 55.5 56 N.A. N.A.
Protein Similarity: 100 95.5 61.4 93.6 N.A. 94.6 95.7 N.A. 91.4 90.3 88.5 80.9 N.A. 70.4 73.3 N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 0 100 N.A. 20 0 80 13.3 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 20 20 N.A. 20 100 N.A. 46.6 20 80 26.6 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. 30.7 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 22 0 0 8 0 8 36 22 15 36 29 15 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 0 0 0 8 0 0 0 0 8 22 29 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 29 29 8 0 8 0 0 8 0 8 8 0 0 8 % K
% Leu: 8 0 8 0 8 29 36 8 8 8 8 29 22 0 0 % L
% Met: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 8 29 50 0 15 0 0 % P
% Gln: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % Q
% Arg: 29 8 15 36 43 15 0 0 0 0 0 8 8 8 0 % R
% Ser: 0 8 29 36 29 36 43 36 36 29 0 15 8 29 36 % S
% Thr: 0 15 8 0 8 8 0 0 0 0 0 0 0 8 29 % T
% Val: 0 0 15 0 0 0 0 0 8 0 0 0 8 8 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _