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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADK
All Species:
23.94
Human Site:
T377
Identified Species:
40.51
UniProt:
O95544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95544
NP_075394.3
446
49228
T377
L
S
P
E
A
R
N
T
A
W
V
S
F
D
G
Chimpanzee
Pan troglodytes
XP_001147420
439
48074
S389
Q
E
I
R
H
G
D
S
I
S
I
T
T
S
C
Rhesus Macaque
Macaca mulatta
XP_001097354
724
78796
T378
L
S
P
E
A
R
N
T
A
W
V
S
F
D
G
Dog
Lupus familis
XP_848833
454
50061
T378
L
S
P
E
A
R
N
T
A
W
V
S
F
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P58058
439
48607
W375
P
E
A
R
N
T
A
W
V
S
F
D
G
R
K
Rat
Rattus norvegicus
NP_001103148
444
49218
W375
P
E
A
R
N
T
A
W
V
S
F
D
G
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508266
441
48900
T375
L
S
P
E
A
R
N
T
A
W
V
S
F
D
G
Chicken
Gallus gallus
NP_001026041
446
49549
T375
L
S
P
D
A
R
N
T
A
W
V
S
F
D
G
Frog
Xenopus laevis
NP_001080015
445
49838
T376
L
S
P
D
A
R
N
T
A
W
V
S
F
D
G
Zebra Danio
Brachydanio rerio
NP_001017580
438
48460
W374
Q
D
A
R
N
T
A
W
V
S
L
D
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097302
450
49903
Q399
P
V
P
C
I
C
A
Q
D
Q
I
S
D
W
F
Honey Bee
Apis mellifera
XP_392018
433
48473
I377
S
L
K
V
T
T
S
I
Y
P
V
P
S
I
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5W3
985
109169
N926
I
P
D
D
A
R
S
N
A
W
V
S
F
D
G
Baker's Yeast
Sacchar. cerevisiae
P32622
495
55855
K418
E
F
F
E
S
I
S
K
N
L
N
W
N
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
61.3
90.7
N.A.
91
91.6
N.A.
86.3
84.9
80.9
72.4
N.A.
55.5
56
N.A.
N.A.
Protein Similarity:
100
95.5
61.4
93.6
N.A.
94.6
95.7
N.A.
91.4
90.3
88.5
80.9
N.A.
70.4
73.3
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
0
0
N.A.
100
93.3
93.3
0
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
0
0
N.A.
100
100
100
6.6
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.7
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
50
0
29
0
50
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
15
% C
% Asp:
0
8
8
22
0
0
8
0
8
0
0
22
8
58
0
% D
% Glu:
8
22
0
36
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
15
0
50
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
22
0
50
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
8
0
8
8
0
15
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
15
% K
% Leu:
43
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
22
0
43
8
8
0
8
0
8
0
0
% N
% Pro:
22
8
50
0
0
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
29
0
50
0
0
0
0
0
0
0
22
15
% R
% Ser:
8
43
0
0
8
0
22
8
0
29
0
58
8
8
0
% S
% Thr:
0
0
0
0
8
29
0
43
0
0
0
8
8
0
0
% T
% Val:
0
8
0
8
0
0
0
0
22
0
58
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
22
0
50
0
8
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _