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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NADK
All Species:
20
Human Site:
Y137
Identified Species:
33.85
UniProt:
O95544
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95544
NP_075394.3
446
49228
Y137
M
E
E
N
M
I
V
Y
V
E
K
K
V
L
E
Chimpanzee
Pan troglodytes
XP_001147420
439
48074
Y137
M
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001097354
724
78796
Y138
E
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
Dog
Lupus familis
XP_848833
454
50061
Y138
E
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P58058
439
48607
Y138
E
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
Rat
Rattus norvegicus
NP_001103148
444
49218
V137
M
E
E
N
N
M
I
V
Y
V
E
K
K
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508266
441
48900
V136
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
D
Chicken
Gallus gallus
NP_001026041
446
49549
Y136
E
E
N
N
M
I
V
Y
V
E
K
K
V
L
E
Frog
Xenopus laevis
NP_001080015
445
49838
V137
T
E
E
K
N
M
I
V
Y
V
E
K
K
V
L
Zebra Danio
Brachydanio rerio
NP_001017580
438
48460
V137
T
Q
Q
K
N
M
I
V
Y
V
E
R
K
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097302
450
49903
R149
V
Q
L
N
E
N
V
R
F
K
A
I
R
D
K
Honey Bee
Apis mellifera
XP_392018
433
48473
L137
V
F
V
E
A
S
V
L
E
D
P
A
L
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5W3
985
109169
A317
Y
Q
T
A
L
D
D
A
I
S
L
G
K
I
T
Baker's Yeast
Sacchar. cerevisiae
P32622
495
55855
I145
I
T
V
Y
V
Q
D
I
F
K
K
S
T
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
61.3
90.7
N.A.
91
91.6
N.A.
86.3
84.9
80.9
72.4
N.A.
55.5
56
N.A.
N.A.
Protein Similarity:
100
95.5
61.4
93.6
N.A.
94.6
95.7
N.A.
91.4
90.3
88.5
80.9
N.A.
70.4
73.3
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
86.6
N.A.
86.6
33.3
N.A.
6.6
86.6
20
0
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
86.6
60
N.A.
40
86.6
46.6
46.6
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
29.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
30.7
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
15
0
0
8
0
0
0
8
8
% D
% Glu:
36
58
22
8
8
0
0
0
15
43
22
0
0
8
43
% E
% Phe:
0
8
0
0
0
0
0
0
15
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
43
22
8
8
0
0
8
0
8
0
% I
% Lys:
0
0
0
15
0
0
0
0
0
22
58
58
29
0
8
% K
% Leu:
0
0
8
0
8
0
0
8
0
0
8
0
15
43
22
% L
% Met:
22
0
0
8
43
22
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
43
58
22
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
22
8
0
0
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
8
% R
% Ser:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% S
% Thr:
15
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% T
% Val:
15
0
15
0
8
8
58
29
43
22
0
8
43
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
8
43
22
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _