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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTRAP
All Species:
24.55
Human Site:
S187
Identified Species:
41.54
UniProt:
O95551
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95551
NP_057698.2
362
40930
S187
T
A
I
M
L
K
K
S
R
V
K
L
K
S
Q
Chimpanzee
Pan troglodytes
XP_518271
384
43414
S217
T
A
I
M
L
K
K
S
R
V
K
L
K
S
Q
Rhesus Macaque
Macaca mulatta
XP_001105245
467
52209
S300
T
A
I
M
L
K
K
S
R
V
K
L
K
S
Q
Dog
Lupus familis
XP_535904
353
40065
S178
T
A
I
M
L
K
K
S
R
V
K
F
K
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX7
370
41015
G197
T
A
I
L
L
K
K
G
R
V
K
F
K
S
Q
Rat
Rattus norvegicus
NP_001030119
366
40775
G193
T
A
I
L
L
K
K
G
R
V
K
F
K
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520864
119
13911
Chicken
Gallus gallus
XP_419093
369
40984
P194
T
A
M
L
L
K
K
P
R
V
K
V
L
K
Q
Frog
Xenopus laevis
NP_001092156
371
41428
S196
T
A
M
M
L
K
K
S
R
V
K
L
I
S
Q
Zebra Danio
Brachydanio rerio
Q5XJA0
369
41485
S196
T
G
I
M
L
R
K
S
R
V
K
F
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493461
362
40875
K193
Y
T
A
I
L
V
S
K
M
F
D
V
E
K
H
Sea Urchin
Strong. purpuratus
XP_001201354
242
26981
S102
C
T
L
V
K
N
S
S
E
S
C
I
T
T
S
Poplar Tree
Populus trichocarpa
XP_002332611
422
47031
S230
G
Y
F
C
M
Q
L
S
K
L
P
V
K
S
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_563894
441
48977
H197
L
R
M
R
A
I
G
H
L
I
Q
L
H
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
73
81.7
N.A.
66.4
65.5
N.A.
23.2
62.8
59.8
46.6
N.A.
N.A.
N.A.
26.2
27.6
Protein Similarity:
100
91.1
74.5
89.2
N.A.
78.3
78.4
N.A.
28.7
76.4
75.7
62.3
N.A.
N.A.
N.A.
49.4
39.5
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
0
60
86.6
60
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
0
80
93.3
66.6
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
24.1
N.A.
N.A.
24.4
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
8
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
29
0
0
8
% F
% Gly:
8
8
0
0
0
0
8
15
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% H
% Ile:
0
0
50
8
0
8
0
0
0
8
0
8
8
0
0
% I
% Lys:
0
0
0
0
8
58
65
8
8
0
65
0
50
15
0
% K
% Leu:
8
0
8
22
72
0
8
0
8
8
0
36
15
0
0
% L
% Met:
0
0
22
43
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
58
% Q
% Arg:
0
8
0
8
0
8
0
0
65
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
58
0
8
0
0
0
58
15
% S
% Thr:
65
15
0
0
0
0
0
0
0
0
0
0
8
8
0
% T
% Val:
0
0
0
8
0
8
0
0
0
65
0
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _