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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTRAP
All Species:
28.79
Human Site:
S254
Identified Species:
48.72
UniProt:
O95551
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95551
NP_057698.2
362
40930
S254
K
M
Q
E
A
P
E
S
A
T
V
I
F
A
G
Chimpanzee
Pan troglodytes
XP_518271
384
43414
S284
K
M
Q
E
A
P
E
S
A
T
V
I
F
A
G
Rhesus Macaque
Macaca mulatta
XP_001105245
467
52209
S367
K
M
Q
E
A
P
E
S
A
T
V
I
F
A
G
Dog
Lupus familis
XP_535904
353
40065
S245
K
M
Q
E
A
P
E
S
A
T
V
I
F
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX7
370
41015
S264
K
M
Q
E
A
P
D
S
T
T
V
I
F
A
G
Rat
Rattus norvegicus
NP_001030119
366
40775
S260
K
M
Q
E
A
T
D
S
T
T
V
I
F
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520864
119
13911
I37
L
G
G
L
P
A
D
I
L
D
I
W
E
F
L
Chicken
Gallus gallus
XP_419093
369
40984
S261
K
M
Q
E
E
S
Q
S
T
T
V
I
F
G
G
Frog
Xenopus laevis
NP_001092156
371
41428
S263
K
M
M
D
A
P
P
S
A
T
V
I
F
G
G
Zebra Danio
Brachydanio rerio
Q5XJA0
369
41485
D263
K
I
K
E
A
P
E
D
A
I
V
I
F
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493461
362
40875
G263
E
I
I
A
Q
N
P
G
A
L
V
F
F
G
G
Sea Urchin
Strong. purpuratus
XP_001201354
242
26981
L160
L
L
Q
F
Q
Q
A
L
G
E
M
Q
I
Q
D
Poplar Tree
Populus trichocarpa
XP_002332611
422
47031
N303
A
I
N
L
L
K
K
N
S
N
V
I
F
C
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_563894
441
48977
A315
R
V
E
Q
A
K
E
A
I
E
I
L
R
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
73
81.7
N.A.
66.4
65.5
N.A.
23.2
62.8
59.8
46.6
N.A.
N.A.
N.A.
26.2
27.6
Protein Similarity:
100
91.1
74.5
89.2
N.A.
78.3
78.4
N.A.
28.7
76.4
75.7
62.3
N.A.
N.A.
N.A.
49.4
39.5
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
0
66.6
73.3
73.3
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
13.3
73.3
80
86.6
N.A.
N.A.
N.A.
40
20
Percent
Protein Identity:
24.1
N.A.
N.A.
24.4
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
65
8
8
8
50
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
22
8
0
8
0
0
0
0
8
% D
% Glu:
8
0
8
58
8
0
43
0
0
15
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
79
8
0
% F
% Gly:
0
8
8
0
0
0
0
8
8
0
0
0
0
22
79
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
22
8
0
0
0
0
8
8
8
15
72
8
0
0
% I
% Lys:
65
0
8
0
0
15
8
0
0
0
0
0
0
0
0
% K
% Leu:
15
8
0
15
8
0
0
8
8
8
0
8
0
0
8
% L
% Met:
0
58
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
8
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
8
50
15
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
58
8
15
8
8
0
0
0
0
8
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
8
0
58
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
22
58
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
79
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _