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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTRAP
All Species:
12.42
Human Site:
T106
Identified Species:
21.03
UniProt:
O95551
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95551
NP_057698.2
362
40930
T106
K
I
S
P
S
E
D
T
Q
Q
E
N
G
S
M
Chimpanzee
Pan troglodytes
XP_518271
384
43414
T136
K
I
S
P
S
E
D
T
Q
Q
E
N
G
S
M
Rhesus Macaque
Macaca mulatta
XP_001105245
467
52209
T219
K
I
S
P
S
E
D
T
Q
Q
E
N
D
S
M
Dog
Lupus familis
XP_535904
353
40065
I97
K
T
S
T
S
E
G
I
Q
Q
E
D
G
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX7
370
41015
T116
L
E
A
S
P
S
G
T
P
L
E
D
S
S
T
Rat
Rattus norvegicus
NP_001030119
366
40775
T112
L
E
T
S
P
S
G
T
P
L
E
D
S
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520864
119
13911
Chicken
Gallus gallus
XP_419093
369
40984
K113
S
S
S
G
A
D
S
K
Q
Q
D
D
D
S
S
Frog
Xenopus laevis
NP_001092156
371
41428
K115
T
S
N
S
S
T
V
K
Q
Q
E
D
E
S
H
Zebra Danio
Brachydanio rerio
Q5XJA0
369
41485
K115
Q
A
E
N
G
T
A
K
S
E
V
E
D
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_493461
362
40875
A112
S
G
A
A
V
M
T
A
E
D
L
K
G
F
E
Sea Urchin
Strong. purpuratus
XP_001201354
242
26981
G21
A
S
R
G
G
P
E
G
E
N
T
N
I
F
R
Poplar Tree
Populus trichocarpa
XP_002332611
422
47031
A149
T
E
D
T
N
S
A
A
V
L
G
S
F
K
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_563894
441
48977
S116
D
A
D
S
S
V
G
S
V
F
F
P
L
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
73
81.7
N.A.
66.4
65.5
N.A.
23.2
62.8
59.8
46.6
N.A.
N.A.
N.A.
26.2
27.6
Protein Similarity:
100
91.1
74.5
89.2
N.A.
78.3
78.4
N.A.
28.7
76.4
75.7
62.3
N.A.
N.A.
N.A.
49.4
39.5
P-Site Identity:
100
100
93.3
66.6
N.A.
20
20
N.A.
0
26.6
33.3
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
33.3
33.3
N.A.
0
53.3
46.6
20
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
24.1
N.A.
N.A.
24.4
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
15
8
8
0
15
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
0
0
8
22
0
0
8
8
36
22
0
0
% D
% Glu:
0
22
8
0
0
29
8
0
15
8
50
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
8
15
0
% F
% Gly:
0
8
0
15
15
0
29
8
0
0
8
0
29
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
22
0
0
0
0
0
8
0
0
0
0
8
0
8
% I
% Lys:
29
0
0
0
0
0
0
22
0
0
0
8
0
8
8
% K
% Leu:
15
0
0
0
0
0
0
0
0
22
8
0
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
29
% M
% Asn:
0
0
8
8
8
0
0
0
0
8
0
29
0
0
0
% N
% Pro:
0
0
0
22
15
8
0
0
15
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
43
43
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
15
% R
% Ser:
15
22
36
29
43
22
8
8
8
0
0
8
15
65
8
% S
% Thr:
15
8
8
15
0
15
8
36
0
0
8
0
0
0
15
% T
% Val:
0
0
0
0
8
8
8
0
15
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _