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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTRAP All Species: 35.76
Human Site: T180 Identified Species: 60.51
UniProt: O95551 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95551 NP_057698.2 362 40930 T180 G H E E G Y F T A I M L K K S
Chimpanzee Pan troglodytes XP_518271 384 43414 T210 G H E E G Y F T A I M L K K S
Rhesus Macaque Macaca mulatta XP_001105245 467 52209 T293 G H E E G Y F T A I M L K K S
Dog Lupus familis XP_535904 353 40065 T171 G H E E G Y F T A I M L K K S
Cat Felis silvestris
Mouse Mus musculus Q9JJX7 370 41015 T190 G N E E G Y F T A I L L K K G
Rat Rattus norvegicus NP_001030119 366 40775 T186 G N E E G Y F T A I L L K K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520864 119 13911
Chicken Gallus gallus XP_419093 369 40984 T187 G N V D G Y F T A M L L K K P
Frog Xenopus laevis NP_001092156 371 41428 T189 G N E D E Y F T A M M L K K S
Zebra Danio Brachydanio rerio Q5XJA0 369 41485 T189 G S D D G Y F T G I M L R K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493461 362 40875 Y186 S N K G C Q Y Y T A I L V S K
Sea Urchin Strong. purpuratus XP_001201354 242 26981 C95 N S I G Y Y T C T L V K N S S
Poplar Tree Populus trichocarpa XP_002332611 422 47031 G223 S E I A S S R G Y F C M Q L S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563894 441 48977 L190 R E D L E L N L R M R A I G H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 73 81.7 N.A. 66.4 65.5 N.A. 23.2 62.8 59.8 46.6 N.A. N.A. N.A. 26.2 27.6
Protein Similarity: 100 91.1 74.5 89.2 N.A. 78.3 78.4 N.A. 28.7 76.4 75.7 62.3 N.A. N.A. N.A. 49.4 39.5
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 0 60 73.3 66.6 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 86.6 93.3 86.6 N.A. N.A. N.A. 33.3 26.6
Percent
Protein Identity: 24.1 N.A. N.A. 24.4 N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. 41.9 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 58 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 0 15 22 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 50 43 15 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 65 0 0 8 0 0 0 0 0 % F
% Gly: 65 0 0 15 58 0 0 8 8 0 0 0 0 8 15 % G
% His: 0 29 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 15 0 0 0 0 0 0 50 8 0 8 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 8 58 65 8 % K
% Leu: 0 0 0 8 0 8 0 8 0 8 22 72 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 22 43 8 0 0 0 % M
% Asn: 8 36 0 0 0 0 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 0 0 0 8 0 8 0 8 0 8 0 0 % R
% Ser: 15 15 0 0 8 8 0 0 0 0 0 0 0 15 58 % S
% Thr: 0 0 0 0 0 0 8 65 15 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 72 8 8 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _