Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTRAP All Species: 9.39
Human Site: Y158 Identified Species: 15.9
UniProt: O95551 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95551 NP_057698.2 362 40930 Y158 Q E V I P P Y Y S Y L K K R S
Chimpanzee Pan troglodytes XP_518271 384 43414 Y188 Q E V I P P Y Y S Y L K K R S
Rhesus Macaque Macaca mulatta XP_001105245 467 52209 Y271 Q E V I P P Y Y S Y L K K R A
Dog Lupus familis XP_535904 353 40065 C149 Q E V I P P Y C S Y L K K R A
Cat Felis silvestris
Mouse Mus musculus Q9JJX7 370 41015 C168 Q E V I P P Y C A Y L K K R A
Rat Rattus norvegicus NP_001030119 366 40775 C164 Q E V I P S Y C A Y L R K R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520864 119 13911
Chicken Gallus gallus XP_419093 369 40984 L165 Q E V I P P Y L C I L Q R R A
Frog Xenopus laevis NP_001092156 371 41428 C167 Q E V I P P Y C E Y L K K R A
Zebra Danio Brachydanio rerio Q5XJA0 369 41485 V167 Q E L I P A Y V Q Y L K K R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493461 362 40875 L164 Q E V V D R D L A P I D K L Q
Sea Urchin Strong. purpuratus XP_001201354 242 26981 L73 V V P T T H T L L K A R L S S
Poplar Tree Populus trichocarpa XP_002332611 422 47031 F201 I P D I Y D I F Q R S S W W K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563894 441 48977 T168 G V A S D S G T P L T C L K I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 73 81.7 N.A. 66.4 65.5 N.A. 23.2 62.8 59.8 46.6 N.A. N.A. N.A. 26.2 27.6
Protein Similarity: 100 91.1 74.5 89.2 N.A. 78.3 78.4 N.A. 28.7 76.4 75.7 62.3 N.A. N.A. N.A. 49.4 39.5
P-Site Identity: 100 100 93.3 86.6 N.A. 80 66.6 N.A. 0 60 80 66.6 N.A. N.A. N.A. 26.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 0 80 86.6 80 N.A. N.A. N.A. 46.6 13.3
Percent
Protein Identity: 24.1 N.A. N.A. 24.4 N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. 41.9 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 22 0 8 0 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 29 8 0 0 8 0 0 0 % C
% Asp: 0 0 8 0 15 8 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 72 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 72 0 0 8 0 0 8 8 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 50 65 8 8 % K
% Leu: 0 0 8 0 0 0 0 22 8 8 65 0 15 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 0 65 50 0 0 8 8 0 0 0 0 0 % P
% Gln: 72 0 0 0 0 0 0 0 15 0 0 8 0 0 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 8 0 15 8 65 0 % R
% Ser: 0 0 0 8 0 15 0 0 29 0 8 8 0 8 22 % S
% Thr: 0 0 0 8 8 0 8 8 0 0 8 0 0 0 0 % T
% Val: 8 15 65 8 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % W
% Tyr: 0 0 0 0 8 0 65 22 0 58 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _