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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETHE1
All Species:
40.91
Human Site:
S106
Identified Species:
81.82
UniProt:
O95571
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95571
NP_055112.2
254
27873
S106
Q
S
V
I
S
R
L
S
G
A
Q
A
D
L
H
Chimpanzee
Pan troglodytes
XP_512716
227
24938
F98
D
S
I
R
F
G
R
F
A
L
E
T
R
A
S
Rhesus Macaque
Macaca mulatta
XP_001101587
255
28010
S106
Q
S
V
I
S
R
L
S
G
A
Q
A
D
L
H
Dog
Lupus familis
XP_855241
254
27781
S106
Q
S
V
I
S
R
L
S
G
A
Q
A
D
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCM0
254
27720
S106
Q
S
V
I
S
R
L
S
G
A
Q
A
D
L
H
Rat
Rattus norvegicus
NP_001099704
254
27658
S106
Q
S
V
I
S
R
L
S
G
A
Q
A
D
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079404
255
28079
S109
K
S
V
I
S
K
D
S
G
A
R
A
D
L
Y
Zebra Danio
Brachydanio rerio
NP_998094
279
30714
S133
K
S
G
I
S
K
H
S
G
A
A
A
D
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725047
279
31383
S130
Q
S
V
I
A
A
A
S
G
A
K
A
D
R
H
Honey Bee
Apis mellifera
XP_393510
276
30982
S124
Q
S
M
I
S
R
S
S
G
A
K
A
D
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307560
265
29233
S103
K
S
I
I
S
K
A
S
K
S
K
A
D
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8L4
256
27855
S99
K
S
V
I
S
K
A
S
G
S
K
A
D
L
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
96.4
92.9
N.A.
90.1
88.1
N.A.
N.A.
N.A.
66.2
59.5
N.A.
53
52.9
N.A.
N.A.
Protein Similarity:
100
89.3
97.2
95.2
N.A.
95.2
93.6
N.A.
N.A.
N.A.
82.7
69.8
N.A.
65.9
65.2
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
N.A.
66.6
53.3
N.A.
66.6
66.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
73.3
N.A.
80
86.6
N.A.
N.A.
Percent
Protein Identity:
55
N.A.
N.A.
58.2
N.A.
N.A.
Protein Similarity:
69
N.A.
N.A.
70.3
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
80
N.A.
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
25
0
9
75
9
92
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
0
0
0
0
92
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
9
0
0
9
0
0
84
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
50
% H
% Ile:
0
0
17
92
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
34
0
0
0
0
34
0
0
9
0
34
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
42
0
0
9
0
0
0
67
17
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
59
0
0
0
0
0
0
0
0
0
42
0
0
0
9
% Q
% Arg:
0
0
0
9
0
50
9
0
0
0
9
0
9
9
0
% R
% Ser:
0
100
0
0
84
0
9
92
0
17
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _