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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETHE1
All Species:
21.21
Human Site:
S14
Identified Species:
42.42
UniProt:
O95571
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95571
NP_055112.2
254
27873
S14
R
V
A
R
R
Q
L
S
Q
R
G
G
S
G
A
Chimpanzee
Pan troglodytes
XP_512716
227
24938
T8
M
F
E
P
V
S
C
T
F
T
Y
L
L
G
D
Rhesus Macaque
Macaca mulatta
XP_001101587
255
28010
S14
R
V
A
R
R
Q
L
S
Q
H
G
G
S
G
A
Dog
Lupus familis
XP_855241
254
27781
S14
R
V
A
G
R
Q
L
S
Q
R
S
G
S
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCM0
254
27720
S14
R
V
A
G
R
R
L
S
Q
Q
S
A
S
G
A
Rat
Rattus norvegicus
NP_001099704
254
27658
S14
R
V
A
G
R
R
L
S
Q
Q
S
A
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079404
255
28079
Y17
A
L
G
Q
C
R
R
Y
S
A
M
A
A
S
S
Zebra Danio
Brachydanio rerio
NP_998094
279
30714
Y41
Y
A
A
S
V
R
L
Y
S
G
L
M
E
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725047
279
31383
P39
S
F
G
T
M
S
L
P
E
R
Q
P
F
S
P
Honey Bee
Apis mellifera
XP_393510
276
30982
T32
C
V
K
C
A
P
L
T
E
P
I
P
F
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307560
265
29233
S9
M
N
Y
T
K
A
A
S
S
Q
A
F
K
N
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8L4
256
27855
S8
M
G
S
S
S
S
F
S
S
S
S
S
K
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
96.4
92.9
N.A.
90.1
88.1
N.A.
N.A.
N.A.
66.2
59.5
N.A.
53
52.9
N.A.
N.A.
Protein Similarity:
100
89.3
97.2
95.2
N.A.
95.2
93.6
N.A.
N.A.
N.A.
82.7
69.8
N.A.
65.9
65.2
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
80
N.A.
66.6
66.6
N.A.
N.A.
N.A.
0
20
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
80
N.A.
80
80
N.A.
N.A.
N.A.
33.3
26.6
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
55
N.A.
N.A.
58.2
N.A.
N.A.
Protein Similarity:
69
N.A.
N.A.
70.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
50
0
9
9
9
0
0
9
9
25
9
0
42
% A
% Cys:
9
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
17
0
0
0
9
0
0
% E
% Phe:
0
17
0
0
0
0
9
0
9
0
0
9
17
0
0
% F
% Gly:
0
9
17
25
0
0
0
0
0
9
17
25
0
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
0
9
0
0
0
0
0
0
0
17
0
17
% K
% Leu:
0
9
0
0
0
0
67
0
0
0
9
9
9
9
9
% L
% Met:
25
0
0
0
9
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
9
0
9
0
9
0
9
0
17
0
9
9
% P
% Gln:
0
0
0
9
0
25
0
0
42
25
9
0
0
0
0
% Q
% Arg:
42
0
0
17
42
34
9
0
0
25
0
0
0
0
0
% R
% Ser:
9
0
9
17
9
25
0
59
34
9
34
9
42
25
9
% S
% Thr:
0
0
0
17
0
0
0
17
0
9
0
0
0
0
0
% T
% Val:
0
50
0
0
17
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
17
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _