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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ETHE1 All Species: 16.06
Human Site: S19 Identified Species: 32.12
UniProt: O95571 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95571 NP_055112.2 254 27873 S19 Q L S Q R G G S G A P I L L R
Chimpanzee Pan troglodytes XP_512716 227 24938 L13 S C T F T Y L L G D R E S R E
Rhesus Macaque Macaca mulatta XP_001101587 255 28010 S19 Q L S Q H G G S G A P I L L R
Dog Lupus familis XP_855241 254 27781 S19 Q L S Q R S G S G V P I L L R
Cat Felis silvestris
Mouse Mus musculus Q9DCM0 254 27720 S19 R L S Q Q S A S G A P V L L R
Rat Rattus norvegicus NP_001099704 254 27658 S19 R L S Q Q S A S G A P V L L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001079404 255 28079 A22 R R Y S A M A A S S G L V F R
Zebra Danio Brachydanio rerio NP_998094 279 30714 E46 R L Y S G L M E P A A P L F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725047 279 31383 F44 S L P E R Q P F S P D F F F R
Honey Bee Apis mellifera XP_393510 276 30982 F37 P L T E P I P F S K D F L F R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002307560 265 29233 K14 A A S S Q A F K N K K L L F R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C8L4 256 27855 K13 S F S S S S S K L L F R Q L F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 96.4 92.9 N.A. 90.1 88.1 N.A. N.A. N.A. 66.2 59.5 N.A. 53 52.9 N.A. N.A.
Protein Similarity: 100 89.3 97.2 95.2 N.A. 95.2 93.6 N.A. N.A. N.A. 82.7 69.8 N.A. 65.9 65.2 N.A. N.A.
P-Site Identity: 100 6.6 93.3 86.6 N.A. 66.6 66.6 N.A. N.A. N.A. 6.6 26.6 N.A. 20 20 N.A. N.A.
P-Site Similarity: 100 13.3 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 40 33.3 N.A. 26.6 33.3 N.A. N.A.
Percent
Protein Identity: 55 N.A. N.A. 58.2 N.A. N.A.
Protein Similarity: 69 N.A. N.A. 70.3 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 9 25 9 0 42 9 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 17 0 0 0 0 % D
% Glu: 0 0 0 17 0 0 0 9 0 0 0 9 0 0 9 % E
% Phe: 0 9 0 9 0 0 9 17 0 0 9 17 9 42 9 % F
% Gly: 0 0 0 0 9 17 25 0 50 0 9 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 25 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 17 0 17 9 0 0 0 0 % K
% Leu: 0 67 0 0 0 9 9 9 9 9 0 17 67 50 0 % L
% Met: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 9 0 9 0 9 0 17 0 9 9 42 9 0 0 0 % P
% Gln: 25 0 0 42 25 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 34 9 0 0 25 0 0 0 0 0 9 9 0 9 84 % R
% Ser: 25 0 59 34 9 34 9 42 25 9 0 0 9 0 0 % S
% Thr: 0 0 17 0 9 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _