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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETHE1
All Species:
31.82
Human Site:
T152
Identified Species:
63.64
UniProt:
O95571
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95571
NP_055112.2
254
27873
T152
N
D
H
S
M
A
F
T
G
D
A
L
L
I
R
Chimpanzee
Pan troglodytes
XP_512716
227
24938
A144
T
D
F
Q
Q
G
C
A
K
T
L
Y
H
S
V
Rhesus Macaque
Macaca mulatta
XP_001101587
255
28010
T152
N
D
H
S
M
A
F
T
G
D
A
L
L
I
R
Dog
Lupus familis
XP_855241
254
27781
T152
N
D
H
S
M
A
F
T
G
D
A
L
L
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCM0
254
27720
T152
N
D
Q
S
M
A
F
T
G
D
A
L
L
I
R
Rat
Rattus norvegicus
NP_001099704
254
27658
T152
N
D
Q
S
M
A
F
T
G
D
A
L
L
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079404
255
28079
T155
N
D
K
S
M
A
F
T
G
D
A
L
L
I
R
Zebra Danio
Brachydanio rerio
NP_998094
279
30714
T179
G
D
Q
R
M
A
F
T
G
D
A
L
L
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725047
279
31383
T176
K
D
Q
G
C
V
F
T
G
D
T
L
L
I
R
Honey Bee
Apis mellifera
XP_393510
276
30982
T170
Y
E
Q
G
I
A
F
T
G
D
A
L
L
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002307560
265
29233
Q149
G
D
G
S
D
Q
P
Q
P
R
M
A
F
T
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8L4
256
27855
Q145
G
E
G
A
D
Q
P
Q
P
R
M
A
F
T
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
96.4
92.9
N.A.
90.1
88.1
N.A.
N.A.
N.A.
66.2
59.5
N.A.
53
52.9
N.A.
N.A.
Protein Similarity:
100
89.3
97.2
95.2
N.A.
95.2
93.6
N.A.
N.A.
N.A.
82.7
69.8
N.A.
65.9
65.2
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
80
N.A.
60
66.6
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
80
N.A.
60
80
N.A.
N.A.
Percent
Protein Identity:
55
N.A.
N.A.
58.2
N.A.
N.A.
Protein Similarity:
69
N.A.
N.A.
70.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
67
0
9
0
0
67
17
0
0
0
% A
% Cys:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
0
0
17
0
0
0
0
75
0
0
0
0
0
% D
% Glu:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
75
0
0
0
0
0
17
0
0
% F
% Gly:
25
0
17
17
0
9
0
0
75
0
0
0
0
0
17
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
75
0
% I
% Lys:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
75
75
0
0
% L
% Met:
0
0
0
0
59
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
42
9
9
17
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
75
% R
% Ser:
0
0
0
59
0
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
9
0
0
0
0
0
0
75
0
9
9
0
0
17
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _