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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSL3 All Species: 21.52
Human Site: S403 Identified Species: 39.44
UniProt: O95573 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95573 NP_004448.2 720 80420 S403 N K V S E M S S F Q R N L F I
Chimpanzee Pan troglodytes XP_001166229 692 77085 S403 N K V S E M S S F Q R N L F I
Rhesus Macaque Macaca mulatta XP_001108259 720 80350 S403 N K V N E M S S F Q R N L F I
Dog Lupus familis XP_851617 720 80340 S403 N K V N E M S S F Q R N L F V
Cat Felis silvestris
Mouse Mus musculus Q9CZW4 720 80488 A403 N K V N E M S A F Q R N L F I
Rat Rattus norvegicus Q63151 720 80440 A403 N K V N E M S A F Q R N L F I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512270 609 67400 F323 P L C D R F V F R K V R S L L
Chicken Gallus gallus XP_422625 713 79313 S394 N K V N E M T S F Q R N L F I
Frog Xenopus laevis Q7ZYC4 739 81601 R403 A K S S T I K R K M A T W A K
Zebra Danio Brachydanio rerio XP_688110 711 78788 S394 T K V E E M S S V Q K T L F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3S9 666 73592 K380 A K S L I M S K V K Q A L G F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84P24 566 61938 I279 L L S L G S T I V V M K R F D
Baker's Yeast Sacchar. cerevisiae P47912 694 77249 Q387 N E L P G W S Q T L F W T V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 98.6 93.8 N.A. 92.7 92.3 N.A. 74.1 82.2 22.3 73.6 N.A. 21.3 N.A. N.A. N.A.
Protein Similarity: 100 94.8 99.7 97.5 N.A. 96.5 96.2 N.A. 79.3 90.8 41.2 83.6 N.A. 40.2 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 0 86.6 13.3 60 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 20 73.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.9 28.6 N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 0 0 0 16 0 0 8 8 0 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 8 0 8 62 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 8 54 0 8 0 0 70 8 % F
% Gly: 0 0 0 0 16 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 47 % I
% Lys: 0 77 0 0 0 0 8 8 8 16 8 8 0 0 8 % K
% Leu: 8 16 8 16 0 0 0 0 0 8 0 0 70 8 8 % L
% Met: 0 0 0 0 0 70 0 0 0 8 8 0 0 0 0 % M
% Asn: 62 0 0 39 0 0 0 0 0 0 0 54 0 0 0 % N
% Pro: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 62 8 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 8 8 0 54 8 8 0 0 % R
% Ser: 0 0 24 24 0 8 70 47 0 0 0 0 8 0 0 % S
% Thr: 8 0 0 0 8 0 16 0 8 0 0 16 8 0 0 % T
% Val: 0 0 62 0 0 0 8 0 24 8 8 0 0 8 16 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _