KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
13.03
Human Site:
S1148
Identified Species:
23.89
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1148
A
C
P
D
P
S
L
S
V
W
R
P
D
I
Y
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1148
A
C
P
D
P
S
L
S
V
W
R
P
D
I
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
A1130
P
C
P
D
P
S
L
A
V
W
R
P
D
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S1155
P
C
P
D
P
S
L
S
V
W
R
P
D
I
Y
Rat
Rattus norvegicus
O54889
1716
194174
S1155
P
C
P
D
P
S
L
S
V
W
R
P
D
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
E867
D
T
A
V
K
T
A
E
T
G
Y
M
Q
R
R
Frog
Xenopus laevis
NP_001082182
1730
195193
A1153
L
L
P
D
P
C
L
A
V
W
R
P
D
L
Y
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
G1141
H
C
P
E
P
C
L
G
L
Y
R
P
D
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
K1115
E
D
K
A
L
Y
R
K
K
Y
A
R
C
P
D
Honey Bee
Apis mellifera
XP_001121092
1665
190473
R1098
W
I
Y
N
K
C
I
R
C
P
D
P
V
M
S
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
P1180
A
V
D
E
R
F
N
P
T
C
K
L
G
A
L
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
Q1149
C
P
D
P
V
S
C
Q
M
R
P
D
R
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
G1134
Y
N
P
A
K
Y
L
G
S
V
S
E
N
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
86.6
N.A.
N.A.
0
66.6
53.3
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
80
73.3
N.A.
6.6
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
16
0
0
8
16
0
0
8
0
0
8
0
% A
% Cys:
8
47
0
0
0
24
8
0
8
8
0
0
8
0
0
% C
% Asp:
8
8
16
47
0
0
0
0
0
0
8
8
54
0
8
% D
% Glu:
8
0
0
16
0
0
0
8
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
16
0
8
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
0
0
47
0
% I
% Lys:
0
0
8
0
24
0
0
8
8
0
8
0
0
0
0
% K
% Leu:
8
8
0
0
8
0
62
0
8
0
0
8
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
24
8
62
8
54
0
0
8
0
8
8
62
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
8
0
8
8
0
8
54
8
8
8
8
% R
% Ser:
0
0
0
0
0
47
0
31
8
0
8
0
0
0
16
% S
% Thr:
0
8
0
0
0
8
0
0
16
0
0
0
0
0
0
% T
% Val:
0
8
0
8
8
0
0
0
47
8
0
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
47
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
16
0
0
0
16
8
0
0
0
39
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _