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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
21.21
Human Site:
S1181
Identified Species:
38.89
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1181
W
A
A
Q
T
E
K
S
Y
E
K
S
E
L
S
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1181
W
A
A
Q
T
E
K
S
Y
E
K
S
E
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S1163
W
A
A
Q
A
E
K
S
Y
K
K
S
E
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S1188
W
A
A
Q
A
E
R
S
Y
K
K
S
E
L
S
Rat
Rattus norvegicus
O54889
1716
194174
S1188
W
A
A
Q
A
E
K
S
H
N
R
S
E
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
F900
S
T
G
D
I
I
Q
F
I
Y
G
G
D
G
L
Frog
Xenopus laevis
NP_001082182
1730
195193
S1186
W
E
Q
Q
R
N
S
S
H
D
M
S
S
L
T
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
S1174
F
N
I
K
Q
E
F
S
A
S
S
E
T
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
Y1148
T
R
K
L
I
T
D
Y
A
K
R
K
P
A
L
Honey Bee
Apis mellifera
XP_001121092
1665
190473
K1131
I
D
E
Y
L
T
N
K
S
K
N
F
I
I
R
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
K1213
V
D
D
E
E
P
P
K
E
V
L
K
R
T
L
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
D1182
L
P
T
S
D
D
A
D
G
T
K
R
E
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
R1167
G
V
N
E
K
K
F
R
A
L
M
Q
L
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
73.3
N.A.
N.A.
0
33.3
13.3
N.A.
0
0
0
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
86.6
N.A.
N.A.
13.3
53.3
26.6
N.A.
13.3
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
39
0
24
0
8
0
24
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
8
8
8
8
8
0
8
0
0
8
8
8
% D
% Glu:
0
8
8
16
8
47
0
0
8
16
0
8
47
0
8
% E
% Phe:
8
0
0
0
0
0
16
8
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
0
8
0
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
16
8
0
0
8
0
0
0
8
8
0
% I
% Lys:
0
0
8
8
8
8
31
16
0
31
39
16
0
8
0
% K
% Leu:
8
0
0
8
8
0
0
0
0
8
8
0
8
47
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
0
8
8
0
0
8
8
0
0
8
8
0
0
0
0
% N
% Pro:
0
8
0
0
0
8
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
47
8
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
0
8
0
8
8
0
0
16
8
8
0
8
% R
% Ser:
8
0
0
8
0
0
8
54
8
8
8
47
8
0
39
% S
% Thr:
8
8
8
0
16
16
0
0
0
8
0
0
8
16
8
% T
% Val:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
31
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _