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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
24.24
Human Site:
S1280
Identified Species:
44.44
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1280
K
A
L
K
R
V
K
S
L
K
K
Q
L
T
R
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1280
K
A
L
K
R
V
K
S
L
K
K
Q
L
T
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S1262
K
A
L
K
R
V
K
S
L
K
K
Q
L
T
R
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S1287
K
A
L
K
K
V
K
S
L
K
K
R
L
T
R
Rat
Rattus norvegicus
O54889
1716
194174
S1287
K
A
L
R
R
V
K
S
L
K
K
Q
L
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
V999
N
G
T
T
E
P
R
V
L
Y
Q
L
D
R
I
Frog
Xenopus laevis
NP_001082182
1730
195193
Q1285
K
A
V
K
R
A
K
Q
L
K
K
R
L
T
R
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
T1273
K
A
L
K
Q
V
K
T
L
R
K
K
I
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
R1247
Q
H
Q
A
E
K
L
R
I
N
L
N
S
V
T
Honey Bee
Apis mellifera
XP_001121092
1665
190473
N1230
K
N
V
I
K
R
S
N
K
L
K
L
K
L
T
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
Y1312
K
R
E
L
D
R
V
Y
L
K
Q
L
L
K
N
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
R1281
I
S
A
K
K
I
G
R
I
C
R
Q
L
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
V1266
S
K
V
L
L
S
E
V
I
D
K
V
I
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
6.6
73.3
66.6
N.A.
0
13.3
26.6
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
20
86.6
100
N.A.
13.3
33.3
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
0
8
0
16
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
24
0
0
0
16
0
8
% I
% Lys:
70
8
0
54
24
8
54
0
8
54
70
8
8
8
0
% K
% Leu:
0
0
47
16
8
0
8
0
70
8
8
24
62
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
8
0
8
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
8
0
0
8
0
0
16
39
0
0
0
% Q
% Arg:
0
8
0
8
39
16
8
16
0
8
8
16
0
8
62
% R
% Ser:
8
8
0
0
0
8
8
39
0
0
0
0
8
8
0
% S
% Thr:
0
0
8
8
0
0
0
8
0
0
0
0
0
54
24
% T
% Val:
0
0
24
0
0
47
8
16
0
0
0
8
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _