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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
9.09
Human Site:
S1386
Identified Species:
16.67
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1386
N
A
G
E
L
G
R
S
R
G
E
Q
E
G
D
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1386
N
T
G
E
L
G
R
S
R
G
E
Q
E
G
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
N1368
N
S
G
E
S
E
R
N
R
G
E
Q
E
G
N
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S1393
D
T
E
D
S
G
R
S
Q
R
E
E
E
R
D
Rat
Rattus norvegicus
O54889
1716
194174
N1393
D
T
E
D
S
G
R
N
R
R
E
E
E
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
K1102
P
D
F
A
R
L
V
K
G
R
I
E
K
T
L
Frog
Xenopus laevis
NP_001082182
1730
195193
E1391
D
G
E
A
Q
G
N
E
E
S
Q
R
A
E
N
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
A1380
R
D
T
S
D
G
G
A
D
R
E
D
N
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
D1350
D
N
D
L
D
N
G
D
E
V
G
R
S
K
A
Honey Bee
Apis mellifera
XP_001121092
1665
190473
P1335
V
L
L
D
Q
I
E
P
D
Q
G
T
E
S
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
D1418
N
R
G
L
Q
G
P
D
N
G
D
S
S
D
E
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
T1387
D
G
G
N
A
A
P
T
Q
D
K
N
G
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
N1369
S
K
R
L
E
E
D
N
D
E
E
Q
S
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
93.3
N.A.
66.6
N.A.
40
40
N.A.
N.A.
0
6.6
20
N.A.
0
6.6
26.6
13.3
P-Site Similarity:
100
93.3
N.A.
86.6
N.A.
66.6
66.6
N.A.
N.A.
13.3
33.3
26.6
N.A.
13.3
13.3
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
8
8
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
16
8
24
16
0
8
16
24
8
8
8
0
8
39
% D
% Glu:
0
0
24
24
8
16
8
8
16
8
54
24
47
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
39
0
0
54
16
0
8
31
16
0
8
31
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
8
0
0
8
0
8
8
8
% K
% Leu:
0
8
8
24
16
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
8
0
8
0
8
8
24
8
0
0
8
8
0
16
% N
% Pro:
8
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
24
0
0
0
16
8
8
31
0
0
0
% Q
% Arg:
8
8
8
0
8
0
39
0
31
31
0
16
0
16
0
% R
% Ser:
8
8
0
8
24
0
0
24
0
8
0
8
24
8
0
% S
% Thr:
0
24
8
0
0
0
0
8
0
0
0
8
0
16
0
% T
% Val:
8
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _