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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
25.76
Human Site:
S706
Identified Species:
47.22
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S706
D
H
I
P
L
N
L
S
G
K
A
K
I
T
G
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S706
D
H
I
P
L
N
L
S
G
K
A
K
I
T
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S688
D
H
I
P
L
S
L
S
G
K
A
K
I
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S713
D
Y
A
P
L
N
L
S
G
K
A
K
I
G
S
Rat
Rattus norvegicus
O54889
1716
194174
T713
D
Y
T
P
L
N
L
T
G
K
A
K
I
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
I477
K
L
S
I
M
A
H
I
A
R
V
K
P
H
R
Frog
Xenopus laevis
NP_001082182
1730
195193
T711
N
L
I
P
L
N
L
T
G
K
A
K
I
G
G
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
T699
N
S
I
P
L
N
L
T
G
K
A
K
I
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
D683
G
Y
E
R
I
N
L
D
S
F
A
K
I
A
G
Honey Bee
Apis mellifera
XP_001121092
1665
190473
K663
I
N
L
T
A
N
A
K
I
N
V
K
Q
W
Q
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
D745
G
K
P
L
I
N
L
D
G
K
A
K
T
P
L
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
K703
L
D
F
I
G
K
S
K
I
N
N
K
S
W
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
T740
T
T
V
L
L
N
V
T
P
P
D
M
P
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
86.6
N.A.
73.3
66.6
N.A.
N.A.
6.6
73.3
73.3
N.A.
40
13.3
40
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
80
80
N.A.
N.A.
20
86.6
86.6
N.A.
53.3
26.6
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
8
0
8
0
70
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
39
8
0
0
0
0
0
16
0
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
62
0
0
0
0
31
47
% G
% His:
0
24
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
39
16
16
0
0
8
16
0
0
0
62
0
8
% I
% Lys:
8
8
0
0
0
8
0
16
0
62
0
93
0
0
0
% K
% Leu:
8
16
8
16
62
0
70
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
8
0
0
0
77
0
0
0
16
8
0
0
0
0
% N
% Pro:
0
0
8
54
0
0
0
0
8
8
0
0
16
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
8
0
0
8
8
31
8
0
0
0
8
8
16
% S
% Thr:
8
8
8
8
0
0
0
31
0
0
0
0
8
16
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% W
% Tyr:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _