KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
30.3
Human Site:
S731
Identified Species:
55.56
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S731
V
P
G
F
N
P
D
S
M
C
E
S
Q
V
I
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S731
V
P
G
F
N
P
D
S
M
C
E
S
Q
V
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S713
V
P
G
F
N
P
D
S
M
C
E
S
Q
V
I
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S738
I
P
D
F
D
P
D
S
M
C
E
S
Q
V
I
Rat
Rattus norvegicus
O54889
1716
194174
S738
V
P
D
F
D
P
D
S
M
C
E
S
Q
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
G502
P
Y
N
A
D
F
D
G
D
E
M
N
L
H
L
Frog
Xenopus laevis
NP_001082182
1730
195193
S736
I
P
G
F
S
P
D
S
M
C
E
S
Q
V
I
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
S724
V
P
G
Y
V
P
E
S
M
C
E
S
Q
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
E708
P
I
C
G
T
N
P
E
G
N
D
L
S
E
S
Honey Bee
Apis mellifera
XP_001121092
1665
190473
T688
T
E
F
S
N
P
N
T
M
S
E
A
E
V
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
S770
P
Q
F
D
M
S
E
S
H
V
V
F
R
Q
G
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
D728
G
G
A
L
V
G
T
D
M
C
E
S
E
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
L765
E
Y
W
G
K
G
S
L
E
N
E
V
L
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
100
N.A.
80
86.6
N.A.
N.A.
6.6
86.6
73.3
N.A.
0
40
6.6
40
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
100
93.3
N.A.
6.6
66.6
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
62
0
0
0
0
0
% C
% Asp:
0
0
16
8
24
0
54
8
8
0
8
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
16
8
8
8
77
0
16
8
0
% E
% Phe:
0
0
16
47
0
8
0
0
0
0
0
8
0
8
0
% F
% Gly:
8
8
39
16
0
16
0
8
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
62
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
0
8
16
0
8
% L
% Met:
0
0
0
0
8
0
0
0
70
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
31
8
8
0
0
16
0
8
0
0
0
% N
% Pro:
24
54
0
0
0
62
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
54
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
8
8
8
62
0
8
0
62
8
0
8
% S
% Thr:
8
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% T
% Val:
39
0
0
0
16
0
0
0
0
8
8
8
0
70
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _