KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
6.67
Human Site:
T360
Identified Species:
12.22
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
T360
E
E
V
A
T
P
T
T
D
E
E
K
D
S
L
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
T360
E
E
V
A
T
P
T
T
D
E
E
K
D
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
K342
C
E
V
S
G
P
A
K
D
E
E
K
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
I367
C
E
M
T
E
L
T
I
D
K
E
N
D
S
S
Rat
Rattus norvegicus
O54889
1716
194174
I367
C
E
M
T
E
I
T
I
D
K
E
N
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
F162
T
C
P
Y
C
G
A
F
N
G
T
V
K
K
C
Frog
Xenopus laevis
NP_001082182
1730
195193
N366
E
L
T
E
S
G
M
N
L
K
E
A
E
V
T
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
Q354
G
T
Q
T
E
L
E
Q
S
S
E
A
P
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
M343
L
N
V
V
L
K
Y
M
K
G
G
Q
E
K
L
Honey Bee
Apis mellifera
XP_001121092
1665
190473
H328
E
G
K
V
V
Y
D
H
I
K
G
N
T
A
I
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
L399
E
T
I
S
A
I
S
L
I
M
K
G
D
T
S
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
V353
N
G
V
M
E
I
D
V
K
L
T
V
K
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
S404
R
D
L
N
D
D
L
S
K
L
Q
K
D
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
60
N.A.
40
40
N.A.
N.A.
0
13.3
6.6
N.A.
13.3
6.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
66.6
N.A.
53.3
53.3
N.A.
N.A.
6.6
33.3
13.3
N.A.
26.6
26.6
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
8
0
16
0
0
0
0
16
0
8
0
% A
% Cys:
24
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
8
8
16
0
39
0
0
0
54
8
0
% D
% Glu:
39
39
0
8
31
0
8
0
0
24
54
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
0
8
16
0
0
0
16
16
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
24
0
16
16
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
8
0
8
24
31
8
31
16
31
8
% K
% Leu:
8
8
8
0
8
16
8
8
8
16
0
0
0
0
24
% L
% Met:
0
0
16
8
0
0
8
8
0
8
0
0
0
0
0
% M
% Asn:
8
8
0
8
0
0
0
8
8
0
0
24
0
0
0
% N
% Pro:
0
0
8
0
0
24
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
8
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
16
8
0
8
8
8
8
0
0
0
39
31
% S
% Thr:
8
16
8
24
16
0
31
16
0
0
16
0
8
8
8
% T
% Val:
0
0
39
16
8
0
0
8
0
0
0
16
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _