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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YEATS4 All Species: 51.52
Human Site: Y74 Identified Species: 75.56
UniProt: O95619 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95619 NP_006521.1 227 26499 Y74 Q F K L H E S Y G N P L R V V
Chimpanzee Pan troglodytes XP_509214 173 20113 E39 R Y F G K K R E E D G H T H Q
Rhesus Macaque Macaca mulatta XP_001117373 222 25560 Y70 Q F K L H E S Y G N P L R V V
Dog Lupus familis XP_531673 223 25962 Y70 Q F K L H E S Y G N P L R V V
Cat Felis silvestris
Mouse Mus musculus Q9CR11 227 26511 Y74 Q F K L H E S Y G N P L R V V
Rat Rattus norvegicus NP_001120999 227 26463 Y74 Q F K L H E S Y G N P L R V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511740 243 28342 Y90 Q F K L H E S Y G N P L R V V
Chicken Gallus gallus NP_001072971 227 26442 Y74 Q F K L H E S Y G N P L R V V
Frog Xenopus laevis NP_001083406 227 26450 Y74 Q F K L H E S Y G N P L R V V
Zebra Danio Brachydanio rerio NP_001002752 226 26516 Y74 Q F K L H E S Y G N P L R V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609086 227 25997 Y70 H F K L H E S Y A N P N R I V
Honey Bee Apis mellifera XP_396159 227 26127 Y73 H F K L H E S Y N N P N R I M
Nematode Worm Caenorhab. elegans NP_502172 211 24930 V73 Y A V P Y R V V E K P P Y E V
Sea Urchin Strong. purpuratus XP_792019 235 27209 Y81 Q F K L H E S Y A N P L R V V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53930 226 25963 Y70 V F K L H D T Y P N P V R S I
Red Bread Mold Neurospora crassa Q7RZK7 309 34649 I73 Q F K L H E S I P N H V R M V
Conservation
Percent
Protein Identity: 100 76.2 78.8 97.3 N.A. 99.5 98.6 N.A. 87.6 97.3 95.5 90.7 N.A. 59.4 64.3 46.2 69.3
Protein Similarity: 100 76.2 82.8 97.8 N.A. 99.5 98.6 N.A. 90.1 100 97.8 95.5 N.A. 73.5 79.3 62.5 82.1
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 73.3 66.6 13.3 93.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 80 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.1 32
Protein Similarity: N.A. N.A. N.A. N.A. 51.9 48.5
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 66.6
P-Site Similarity: N.A. N.A. N.A. N.A. 80 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 13 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 82 0 7 13 0 0 0 0 7 0 % E
% Phe: 0 88 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 57 0 7 0 0 0 0 % G
% His: 13 0 0 0 88 0 0 0 0 0 7 7 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 13 7 % I
% Lys: 0 0 88 0 7 7 0 0 0 7 0 0 0 0 0 % K
% Leu: 0 0 0 88 0 0 0 0 0 0 0 63 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 0 0 0 7 88 0 13 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 13 0 88 7 0 0 0 % P
% Gln: 69 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 7 0 0 0 0 7 7 0 0 0 0 0 88 0 0 % R
% Ser: 0 0 0 0 0 0 82 0 0 0 0 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % T
% Val: 7 0 7 0 0 0 7 7 0 0 0 13 0 63 82 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 7 0 0 82 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _