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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY5
All Species:
16.67
Human Site:
S403
Identified Species:
33.33
UniProt:
O95622
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95622
NP_899200.1
1261
138908
S403
T
H
Y
P
A
E
V
S
Q
R
Q
A
F
Q
E
Chimpanzee
Pan troglodytes
XP_509033
1166
130086
K353
Q
H
V
A
M
E
M
K
E
D
I
N
T
K
K
Rhesus Macaque
Macaca mulatta
XP_001106344
1157
128101
Y357
D
M
M
F
H
K
I
Y
I
Q
K
H
D
N
V
Dog
Lupus familis
XP_545134
1205
134641
S388
E
G
F
T
S
L
A
S
Q
C
T
A
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P84309
1262
139103
S404
T
H
Y
P
A
E
V
S
Q
R
Q
A
F
Q
E
Rat
Rattus norvegicus
Q04400
1262
139160
S404
T
H
Y
P
A
E
V
S
Q
R
Q
A
F
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511957
593
65761
Chicken
Gallus gallus
NP_989962
1211
136481
S355
T
H
Y
P
A
E
V
S
Q
R
Q
A
F
Q
E
Frog
Xenopus laevis
P98999
1305
145393
F379
T
P
I
I
F
R
P
F
K
M
Q
R
I
E
Q
Zebra Danio
Brachydanio rerio
XP_001922749
1174
131279
K353
R
H
V
A
M
E
M
K
A
D
I
N
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097622
1695
188364
A506
T
H
W
P
K
E
K
A
Q
R
K
A
F
I
E
Honey Bee
Apis mellifera
XP_001122246
1014
113539
L252
R
H
E
N
V
S
I
L
F
A
D
I
C
G
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.8
90.9
78.5
N.A.
94.7
94.8
N.A.
32.4
78.5
26.5
63.2
N.A.
26.7
40.6
N.A.
N.A.
Protein Similarity:
100
72.4
91.1
81.5
N.A.
96.8
96.6
N.A.
39
84.6
44.2
73.4
N.A.
41.7
54.3
N.A.
N.A.
P-Site Identity:
100
13.3
0
20
N.A.
100
100
N.A.
0
100
13.3
13.3
N.A.
60
6.6
N.A.
N.A.
P-Site Similarity:
100
40
26.6
40
N.A.
100
100
N.A.
0
100
33.3
33.3
N.A.
80
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
34
0
9
9
9
9
0
50
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
17
9
0
9
0
0
% D
% Glu:
9
0
9
0
0
59
0
0
9
0
0
0
0
17
42
% E
% Phe:
0
0
9
9
9
0
0
9
9
0
0
0
42
0
9
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
67
0
0
9
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
9
9
0
0
17
0
9
0
17
9
9
9
0
% I
% Lys:
0
0
0
0
9
9
9
17
9
0
17
0
0
17
17
% K
% Leu:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% L
% Met:
0
9
9
0
17
0
17
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
17
0
9
0
% N
% Pro:
0
9
0
42
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
50
9
42
0
9
34
9
% Q
% Arg:
17
0
0
0
0
9
0
0
0
42
0
9
0
0
0
% R
% Ser:
0
0
0
0
9
9
0
42
0
0
0
0
0
0
0
% S
% Thr:
50
0
0
9
0
0
0
0
0
0
9
0
9
0
0
% T
% Val:
0
0
17
0
9
0
34
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _