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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY5
All Species:
34.24
Human Site:
Y1084
Identified Species:
68.48
UniProt:
O95622
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95622
NP_899200.1
1261
138908
Y1084
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Chimpanzee
Pan troglodytes
XP_509033
1166
130086
Y990
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Rhesus Macaque
Macaca mulatta
XP_001106344
1157
128101
Y980
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Dog
Lupus familis
XP_545134
1205
134641
Y1028
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Cat
Felis silvestris
Mouse
Mus musculus
P84309
1262
139103
Y1085
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Rat
Rattus norvegicus
Q04400
1262
139160
Y1085
I
A
N
F
S
E
F
Y
V
E
L
E
A
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511957
593
65761
K448
E
P
F
R
Q
L
E
K
I
K
T
I
G
S
T
Chicken
Gallus gallus
NP_989962
1211
136481
Y1035
I
S
N
F
S
E
F
Y
V
E
L
E
A
N
N
Frog
Xenopus laevis
P98999
1305
145393
Y1062
I
V
N
F
S
E
F
Y
E
E
N
Y
E
G
G
Zebra Danio
Brachydanio rerio
XP_001922749
1174
131279
Y997
I
S
N
F
S
E
F
Y
V
E
L
E
A
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097622
1695
188364
V1158
L
E
G
N
N
E
G
V
E
C
L
R
L
L
N
Honey Bee
Apis mellifera
XP_001122246
1014
113539
H869
C
D
M
K
D
Y
K
H
V
T
A
M
A
D
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.8
90.9
78.5
N.A.
94.7
94.8
N.A.
32.4
78.5
26.5
63.2
N.A.
26.7
40.6
N.A.
N.A.
Protein Similarity:
100
72.4
91.1
81.5
N.A.
96.8
96.6
N.A.
39
84.6
44.2
73.4
N.A.
41.7
54.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
93.3
53.3
93.3
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
53.3
100
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
0
0
0
0
0
9
0
75
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
9
0
0
0
84
9
0
17
75
0
67
9
0
0
% E
% Phe:
0
0
9
75
0
0
75
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
9
0
0
0
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
75
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
0
0
9
9
0
9
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
9
0
0
0
0
75
0
9
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
75
9
9
0
0
0
0
0
9
0
0
67
75
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
17
0
0
75
0
0
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
9
% T
% Val:
0
9
0
0
0
0
0
9
75
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
75
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _