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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT4
All Species:
37.27
Human Site:
S435
Identified Species:
68.33
UniProt:
O95628
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95628
NP_001008226.1
575
63510
S435
Q
P
S
L
S
P
T
S
L
Q
N
S
S
S
H
Chimpanzee
Pan troglodytes
XP_001145560
572
63013
S432
Q
P
S
L
S
P
T
S
L
Q
N
S
S
S
H
Rhesus Macaque
Macaca mulatta
XP_001105498
572
63013
S432
Q
P
S
L
S
P
T
S
L
Q
N
S
S
S
H
Dog
Lupus familis
XP_859452
572
63053
S432
Q
P
S
L
S
P
T
S
L
Q
N
S
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BT14
575
63456
S435
Q
P
S
L
S
P
T
S
L
Q
N
A
S
S
H
Rat
Rattus norvegicus
NP_001032871
710
77747
S432
Q
P
S
L
S
S
T
S
L
Q
N
S
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512368
631
69349
S432
Q
P
S
L
S
P
T
S
L
Q
N
A
P
S
H
Chicken
Gallus gallus
NP_001012829
762
83565
S484
Q
P
S
L
S
P
T
S
L
Q
N
P
S
P
H
Frog
Xenopus laevis
NP_001080612
712
78417
S435
Q
P
S
L
S
P
T
S
V
Q
N
P
N
P
H
Zebra Danio
Brachydanio rerio
NP_957463
798
86410
E435
S
D
W
P
T
A
P
E
P
Q
S
L
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392724
529
59085
S392
G
T
Q
N
N
V
Q
S
Q
I
N
G
Q
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780160
657
71694
A433
V
Q
S
I
P
D
L
A
P
P
P
V
T
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34909
587
65335
S446
N
Y
Q
K
R
P
I
S
I
K
S
N
I
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
98.7
N.A.
98.7
77.4
N.A.
84.4
71.6
72.8
55.3
N.A.
N.A.
40.8
N.A.
41.8
Protein Similarity:
100
99.3
99.3
99.1
N.A.
99.1
79.1
N.A.
87
73.3
75.4
61.2
N.A.
N.A.
55.8
N.A.
54
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
73.3
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
86.6
86.6
26.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
16
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% H
% Ile:
0
0
0
8
0
0
8
0
8
8
0
0
8
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
70
0
0
8
0
62
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
0
0
0
0
0
77
8
8
0
0
% N
% Pro:
0
70
0
8
8
70
8
0
16
8
8
16
8
16
0
% P
% Gln:
70
8
16
0
0
0
8
0
8
77
0
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
77
0
70
8
0
85
0
0
16
39
54
54
8
% S
% Thr:
0
8
0
0
8
0
70
0
0
0
0
0
8
8
8
% T
% Val:
8
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _