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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT4
All Species:
33.03
Human Site:
Y498
Identified Species:
60.56
UniProt:
O95628
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95628
NP_001008226.1
575
63510
Y498
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Chimpanzee
Pan troglodytes
XP_001145560
572
63013
Y495
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Rhesus Macaque
Macaca mulatta
XP_001105498
572
63013
Y495
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Dog
Lupus familis
XP_859452
572
63053
Y495
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BT14
575
63456
Y498
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Rat
Rattus norvegicus
NP_001032871
710
77747
Y495
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512368
631
69349
Y497
F
P
G
Q
G
A
R
Y
P
W
M
A
F
P
R
Chicken
Gallus gallus
NP_001012829
762
83565
Y547
F
P
G
Q
A
A
R
Y
P
W
M
A
F
P
R
Frog
Xenopus laevis
NP_001080612
712
78417
H508
F
P
R
N
N
I
M
H
L
N
H
T
A
N
P
Zebra Danio
Brachydanio rerio
NP_957463
798
86410
S566
F
P
G
Q
A
Q
S
S
R
H
S
W
M
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392724
529
59085
K454
Q
Q
Q
Q
Q
N
N
K
G
S
K
S
V
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780160
657
71694
M514
A
P
S
E
L
L
P
M
D
G
H
T
T
D
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34909
587
65335
N510
Q
S
V
N
V
G
V
N
D
N
I
T
I
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
99.1
98.7
N.A.
98.7
77.4
N.A.
84.4
71.6
72.8
55.3
N.A.
N.A.
40.8
N.A.
41.8
Protein Similarity:
100
99.3
99.3
99.1
N.A.
99.1
79.1
N.A.
87
73.3
75.4
61.2
N.A.
N.A.
55.8
N.A.
54
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
13.3
33.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
20
33.3
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
62
62
0
0
0
0
0
62
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
8
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
77
0
0
0
0
0
0
0
0
0
0
0
62
0
0
% F
% Gly:
0
0
70
0
8
8
0
0
8
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
8
0
0
62
0
8
0
8
% M
% Asn:
0
0
0
16
8
8
8
8
0
16
0
0
0
8
0
% N
% Pro:
0
85
0
0
0
0
8
0
62
0
0
0
0
62
8
% P
% Gln:
16
8
8
77
8
8
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
8
0
0
0
62
0
8
0
0
0
0
0
62
% R
% Ser:
0
8
8
0
0
0
8
8
0
8
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
24
8
8
0
% T
% Val:
0
0
8
0
8
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
62
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _