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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FSTL3 All Species: 4.24
Human Site: T246 Identified Species: 9.33
UniProt: O95633 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95633 NP_005851.1 263 27663 T246 H A G S C A G T P E E P P G G
Chimpanzee Pan troglodytes XP_517768 739 82086 K638 Y E G K C I T K S C E D I Q C
Rhesus Macaque Macaca mulatta XP_001117132 502 52903 T485 H A G S C A G T P E E P P D G
Dog Lupus familis XP_855222 261 27127 A214 H P G S C A G A A R S G E Q R
Cat Felis silvestris
Mouse Mus musculus Q9EQC7 256 27253 H237 G R S I G V R H P G I C T G G
Rat Rattus norvegicus Q99PW7 256 27091 H237 G R S I G V R H P G I C T G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507223 338 37497 A236 Y E G K C I K A K S C E D I Q
Chicken Gallus gallus Q90844 343 38174 A241 Y E G K C I K A K S C E D I Q
Frog Xenopus laevis P31515 341 37524 A242 Y E G K C I K A K S C E D I Q
Zebra Danio Brachydanio rerio Q9YHV4 322 35499 K246 E G K C I K A K S C D D I H C
Tiger Blowfish Takifugu rubipres NP_001032947 321 35424 K245 E G K C I K A K S C E D I Q C
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.2 49.2 70.7 N.A. 82.1 82.1 N.A. 35.7 35.5 36 37.5 36.1 N.A. N.A. N.A. N.A.
Protein Similarity: 100 27.2 50.2 76 N.A. 87 87.4 N.A. 49.4 49.5 50.4 51.8 51 N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 93.3 40 N.A. 20 20 N.A. 13.3 13.3 13.3 0 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 93.3 40 N.A. 20 20 N.A. 20 20 20 6.6 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 28 19 37 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 19 64 0 0 0 0 28 28 19 0 0 28 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 28 28 10 0 % D
% Glu: 19 37 0 0 0 0 0 0 0 19 37 28 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 19 64 0 19 0 28 0 0 19 0 10 0 28 37 % G
% His: 28 0 0 0 0 0 0 19 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 19 19 37 0 0 0 0 19 0 28 28 0 % I
% Lys: 0 0 19 37 0 19 28 28 28 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 37 0 0 19 19 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 28 % Q
% Arg: 0 19 0 0 0 0 19 0 0 10 0 0 0 0 10 % R
% Ser: 0 0 19 28 0 0 0 0 28 28 10 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 19 0 0 0 0 19 0 0 % T
% Val: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _