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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF4
All Species:
8.48
Human Site:
S192
Identified Species:
16.97
UniProt:
O95639
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95639
NP_001075028.1
269
30255
S192
T
Q
P
P
A
K
Q
S
N
N
P
P
L
Q
R
Chimpanzee
Pan troglodytes
XP_519234
269
30294
S192
T
Q
P
P
A
K
Q
S
N
N
P
P
L
Q
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850149
269
30210
S192
T
Q
P
A
T
K
Q
S
N
N
P
P
L
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQZ5
211
23635
P135
P
S
C
K
F
M
H
P
R
F
E
L
P
M
G
Rat
Rattus norvegicus
Q5FVR7
243
27400
H166
G
P
S
C
K
F
M
H
P
R
F
E
L
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512096
280
31237
N204
T
L
P
L
A
K
Q
N
N
N
P
P
L
Q
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DJP7
269
30474
N192
T
Q
N
Q
Q
K
Q
N
N
N
Q
V
L
Q
R
Zebra Danio
Brachydanio rerio
NP_571084
271
30746
Q192
V
Q
T
Q
Q
K
Q
Q
N
M
Q
P
I
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477156
296
33482
C194
K
L
P
T
C
H
Y
C
G
E
L
G
H
K
A
Honey Bee
Apis mellifera
XP_396082
286
32606
C192
V
M
I
T
C
H
F
C
G
E
G
G
H
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06102
208
24535
C132
E
N
Y
E
M
G
F
C
P
L
G
S
S
C
P
Red Bread Mold
Neurospora crassa
Q7SGR2
317
35182
Q224
G
D
Q
M
L
L
Q
Q
Q
Q
Q
Q
Q
Q
Q
Conservation
Percent
Protein Identity:
100
99.2
N.A.
98.8
N.A.
77.6
89.5
N.A.
83.2
N.A.
90.3
85.2
N.A.
54.3
56.2
N.A.
N.A.
Protein Similarity:
100
99.2
N.A.
98.8
N.A.
77.6
89.5
N.A.
86
N.A.
94.8
90.4
N.A.
66.5
70.2
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
0
6.6
N.A.
80
N.A.
60
40
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
0
6.6
N.A.
86.6
N.A.
66.6
46.6
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33
31.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
44.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
25
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
9
9
17
0
0
25
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
9
0
0
0
0
0
17
9
9
0
0
0
% E
% Phe:
0
0
0
0
9
9
17
0
0
9
9
0
0
0
0
% F
% Gly:
17
0
0
0
0
9
0
0
17
0
17
17
0
0
9
% G
% His:
0
0
0
0
0
17
9
9
0
0
0
0
17
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
9
9
50
0
0
0
0
0
0
0
17
0
% K
% Leu:
0
17
0
9
9
9
0
0
0
9
9
9
50
0
0
% L
% Met:
0
9
0
9
9
9
9
0
0
9
0
0
0
9
9
% M
% Asn:
0
9
9
0
0
0
0
17
50
42
0
0
0
9
0
% N
% Pro:
9
9
42
17
0
0
0
9
17
0
34
42
9
9
9
% P
% Gln:
0
42
9
17
17
0
59
17
9
9
25
9
9
50
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
50
% R
% Ser:
0
9
9
0
0
0
0
25
0
0
0
9
9
0
0
% S
% Thr:
42
0
9
17
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _