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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS3
All Species:
8.18
Human Site:
S213
Identified Species:
15
UniProt:
O95661
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95661
NP_004666.1
229
25861
S213
L
Q
E
P
E
K
K
S
Q
M
P
N
T
T
E
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
S183
L
S
Q
G
E
E
N
S
I
K
R
I
E
P
Q
Rhesus Macaque
Macaca mulatta
XP_001095631
228
26121
Q213
Q
E
P
E
K
E
S
Q
M
P
N
T
T
E
K
Dog
Lupus familis
XP_541313
208
23428
S192
L
Q
I
D
G
K
K
S
K
Q
Q
K
R
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5PR73
199
22479
S183
L
Q
I
D
G
K
K
S
K
Q
Q
K
R
K
E
Rat
Rattus norvegicus
Q62636
184
20779
V171
Q
I
N
R
K
T
P
V
P
G
K
A
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513649
198
22370
Q185
D
G
K
K
A
K
Q
Q
K
K
K
D
K
L
K
Chicken
Gallus gallus
XP_423026
199
22563
S183
L
Q
I
D
G
K
K
S
K
Q
Q
K
R
K
E
Frog
Xenopus laevis
Q7ZXH7
184
20815
V171
Q
I
N
R
K
T
P
V
P
G
K
A
R
K
K
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
V171
Q
I
N
R
K
T
P
V
T
G
K
P
R
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
K171
I
N
K
K
S
P
E
K
K
Q
K
K
P
K
K
Honey Bee
Apis mellifera
XP_001121695
205
22930
N185
L
Q
P
V
Q
S
N
N
A
I
S
L
K
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
Q185
E
T
K
K
T
K
S
Q
K
R
R
E
K
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.4
91.6
43.2
N.A.
42.3
24.4
N.A.
44.5
43.6
24.4
24.8
N.A.
26.2
36.6
N.A.
41.9
Protein Similarity:
100
55.9
95.6
60.7
N.A.
58.5
42.3
N.A.
59.8
59.3
42.3
42.3
N.A.
44.5
56.7
N.A.
59.3
P-Site Identity:
100
20
6.6
40
N.A.
40
0
N.A.
6.6
40
0
0
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
40
33.3
46.6
N.A.
46.6
13.3
N.A.
40
46.6
13.3
13.3
N.A.
33.3
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
24
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
8
8
8
16
16
8
0
0
0
0
8
8
16
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
24
0
0
0
0
24
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
24
24
0
0
0
0
0
8
8
0
8
0
0
0
% I
% Lys:
0
0
24
24
31
47
31
8
47
16
39
31
24
54
62
% K
% Leu:
47
0
0
0
0
0
0
0
0
0
0
8
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
8
24
0
0
0
16
8
0
0
8
8
0
0
0
% N
% Pro:
0
0
16
8
0
8
24
0
16
8
8
8
8
8
0
% P
% Gln:
31
39
8
0
8
0
8
24
8
31
24
0
0
0
8
% Q
% Arg:
0
0
0
24
0
0
0
0
0
8
16
0
47
0
0
% R
% Ser:
0
8
0
0
8
8
16
39
0
0
8
0
0
0
0
% S
% Thr:
0
8
0
0
8
24
0
0
8
0
0
8
16
8
0
% T
% Val:
0
0
0
8
0
0
0
24
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _