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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NTSR2
All Species:
6.67
Human Site:
S291
Identified Species:
12.22
UniProt:
O95665
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95665
NP_036476.1
410
45413
S291
K
D
V
R
R
I
R
S
L
Q
R
S
V
Q
V
Chimpanzee
Pan troglodytes
XP_514769
418
46021
Q297
L
S
P
G
R
A
E
Q
T
R
H
P
A
R
V
Rhesus Macaque
Macaca mulatta
Q28524
418
44639
A290
L
P
L
R
E
H
R
A
L
C
T
L
G
L
I
Dog
Lupus familis
XP_540085
379
41783
E262
H
M
E
L
M
S
E
E
R
R
T
L
P
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P70310
417
46519
S292
K
D
A
S
Q
I
R
S
L
Q
H
S
A
Q
V
Rat
Rattus norvegicus
Q63384
416
46247
S291
K
D
A
S
Q
I
R
S
L
Q
H
S
A
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506365
416
46666
A295
M
E
P
S
R
V
Q
A
L
K
H
G
V
R
V
Chicken
Gallus gallus
XP_426705
508
57169
I322
D
R
L
V
W
S
F
I
S
T
W
T
G
P
M
Frog
Xenopus laevis
P70031
453
51139
A337
N
S
E
A
K
L
M
A
K
K
R
V
I
R
M
Zebra Danio
Brachydanio rerio
Q1JPS6
500
54471
L362
I
P
V
L
R
P
I
L
R
V
K
E
K
D
L
Tiger Blowfish
Takifugu rubipres
NP_001098705
417
46824
K287
V
M
M
A
A
L
P
K
S
S
W
T
A
S
F
Fruit Fly
Dros. melanogaster
Q8ITC7
477
53986
F321
F
H
L
Q
R
L
I
F
L
Y
A
K
N
M
D
Honey Bee
Apis mellifera
NP_001091688
581
66278
Q312
R
L
L
A
V
Y
A
Q
N
S
K
D
K
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
25.6
73.9
N.A.
74
78.1
N.A.
38.2
22.2
20
20.2
22
21.3
20.8
N.A.
N.A.
Protein Similarity:
100
56.4
39.9
80.2
N.A.
81.7
85.5
N.A.
61
40.3
38.1
35.2
44.1
38.3
36.3
N.A.
N.A.
P-Site Identity:
100
13.3
20
0
N.A.
66.6
66.6
N.A.
26.6
0
6.6
13.3
0
13.3
0
N.A.
N.A.
P-Site Similarity:
100
26.6
40
6.6
N.A.
73.3
73.3
N.A.
66.6
20
53.3
26.6
20
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
24
8
8
8
24
0
0
8
0
31
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
24
0
0
0
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
8
16
0
8
0
16
8
0
0
0
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
8
16
0
8
% G
% His:
8
8
0
0
0
8
0
0
0
0
31
0
0
0
0
% H
% Ile:
8
0
0
0
0
24
16
8
0
0
0
0
8
0
8
% I
% Lys:
24
0
0
0
8
0
0
8
8
16
16
8
16
0
0
% K
% Leu:
16
8
31
16
0
24
0
8
47
0
0
16
0
16
8
% L
% Met:
8
16
8
0
8
0
8
0
0
0
0
0
0
8
16
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
16
16
0
0
8
8
0
0
0
0
8
8
16
0
% P
% Gln:
0
0
0
8
16
0
8
16
0
24
0
0
0
24
0
% Q
% Arg:
8
8
0
16
39
0
31
0
16
16
16
0
0
24
0
% R
% Ser:
0
16
0
24
0
16
0
24
16
16
0
24
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
16
16
0
0
0
% T
% Val:
8
0
16
8
8
8
0
0
0
8
0
8
16
0
39
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
16
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _