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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASMTL All Species: 3.64
Human Site: S228 Identified Species: 10
UniProt: O95671 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95671 NP_004183.2 621 68857 S228 R R S V K H D S I P A A D T F
Chimpanzee Pan troglodytes XP_001137782 374 41360 P39 G L R F E V V P S K F K E K L
Rhesus Macaque Macaca mulatta Q8HZJ0 345 38141 R10 S S G D D G Y R L L N E Y T N
Dog Lupus familis XP_851655 742 79048 S345 V R R V K H D S I P A V D T F
Cat Felis silvestris
Mouse Mus musculus NP_081215 233 25048
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506357 823 88920 Q436 S S D G Q P A Q P P A S A H C
Chicken Gallus gallus Q92056 346 39117 Q11 T E D L D Y P Q I I F Q Y S N
Frog Xenopus laevis NP_001085814 625 70101 N237 P Y V E T F E N L S D V E K D
Zebra Danio Brachydanio rerio NP_998676 632 70767 L228 A H K I K R D L D E A W T L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.3 27.2 49 N.A. 21.7 N.A. N.A. 43.2 24.4 58.2 53.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 58.2 36.5 60.2 N.A. 28.8 N.A. N.A. 52.3 36.7 72.8 69.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 80 N.A. 0 N.A. N.A. 13.3 6.6 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 13.3 80 N.A. 0 N.A. N.A. 26.6 26.6 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 12 0 0 0 45 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % C
% Asp: 0 0 23 12 23 0 34 0 12 0 12 0 23 0 12 % D
% Glu: 0 12 0 12 12 0 12 0 0 12 0 12 23 0 0 % E
% Phe: 0 0 0 12 0 12 0 0 0 0 23 0 0 0 23 % F
% Gly: 12 0 12 12 0 12 0 0 0 0 0 0 0 0 0 % G
% His: 0 12 0 0 0 23 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 0 0 12 0 0 0 0 34 12 0 0 0 0 0 % I
% Lys: 0 0 12 0 34 0 0 0 0 12 0 12 0 23 0 % K
% Leu: 0 12 0 12 0 0 0 12 23 12 0 0 0 12 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 12 0 0 0 23 % N
% Pro: 12 0 0 0 0 12 12 12 12 34 0 0 0 0 0 % P
% Gln: 0 0 0 0 12 0 0 23 0 0 0 12 0 0 0 % Q
% Arg: 12 23 23 0 0 12 0 12 0 0 0 0 0 0 0 % R
% Ser: 23 23 12 0 0 0 0 23 12 12 0 12 0 12 0 % S
% Thr: 12 0 0 0 12 0 0 0 0 0 0 0 12 34 0 % T
% Val: 12 0 12 23 0 12 12 0 0 0 0 23 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 0 12 0 0 0 12 12 0 0 0 0 0 23 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _