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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDS2 All Species: 13.33
Human Site: S41 Identified Species: 24.44
UniProt: O95674 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95674 NP_003809.1 445 51418 S41 D S E S R A E S A P L P V S A
Chimpanzee Pan troglodytes XP_001165937 445 51414 S41 D S E S R A E S A P L P V S A
Rhesus Macaque Macaca mulatta XP_001104375 460 52839 I58 D S R T D S D I P E I P A S S
Dog Lupus familis XP_542903 454 52058 A50 D S E S R A E A A P L S A S T
Cat Felis silvestris
Mouse Mus musculus Q99L43 444 51295 T40 D S E S R A E T A P L P T S V
Rat Rattus norvegicus Q91XU8 443 51304 T40 D S E S R A E T A P P P T S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513442 748 84077 I155 D S R T D S D I P E V P Q S S
Chicken Gallus gallus XP_417669 448 51740 G45 E S K S E F G G S P P V P T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957480 444 51048 K40 G A S D S E T K P E V P V S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P56079 447 51493 A55 E K F V D E L A K N L P Q G T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53439 455 52423 T57 E D R L E R L T Q A I P Q D K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04928 421 48641 G30 S N E V V T D G D K V N A S P
Baker's Yeast Sacchar. cerevisiae P38221 457 51804 A39 Q E E L H K D A S E S V T P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 67.3 92.2 N.A. 96.1 94.6 N.A. 44.6 90.1 N.A. 81.5 N.A. 59.5 N.A. 51.8 N.A.
Protein Similarity: 100 99.7 80.6 93.1 N.A. 97.3 96.8 N.A. 51.2 94.6 N.A. 90.7 N.A. 74.2 N.A. 66.1 N.A.
P-Site Identity: 100 100 26.6 73.3 N.A. 80 73.3 N.A. 26.6 20 N.A. 26.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 60 80 N.A. 86.6 80 N.A. 60 53.3 N.A. 40 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 54.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 39 0 24 39 8 0 0 24 0 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 8 0 8 24 0 31 0 8 0 0 0 0 8 0 % D
% Glu: 24 8 54 0 16 16 39 0 0 31 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 16 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 16 0 0 16 0 0 0 8 % I
% Lys: 0 8 8 0 0 8 0 8 8 8 0 0 0 0 8 % K
% Leu: 0 0 0 16 0 0 16 0 0 0 39 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 24 47 16 70 8 8 8 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 0 0 24 0 0 % Q
% Arg: 0 0 24 0 39 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 62 8 47 8 16 0 16 16 0 8 8 0 70 24 % S
% Thr: 0 0 0 16 0 8 8 24 0 0 0 0 24 8 16 % T
% Val: 0 0 0 16 8 0 0 0 0 0 24 16 24 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _