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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDS2 All Species: 8.57
Human Site: T442 Identified Species: 15.71
UniProt: O95674 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95674 NP_003809.1 445 51418 T442 K G M L T S T T E D E _ _ _ _
Chimpanzee Pan troglodytes XP_001165937 445 51414 T442 K G M L T S T T E D K _ _ _ _
Rhesus Macaque Macaca mulatta XP_001104375 460 52839
Dog Lupus familis XP_542903 454 52058 T451 K G M L T V A T E D E _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q99L43 444 51295 L441 K G I L T S A L E D E _ _ _ _
Rat Rattus norvegicus Q91XU8 443 51304
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513442 748 84077 L556 E G I L P A A L P R G S S L P
Chicken Gallus gallus XP_417669 448 51740
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_957480 444 51048 E441 K G L L P A L E E A A _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P56079 447 51493 D444 S L K D N L G D M L T _ _ _ _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53439 455 52423
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04928 421 48641
Baker's Yeast Sacchar. cerevisiae P38221 457 51804 S435 L S K K G I I S A K N F E K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 67.3 92.2 N.A. 96.1 94.6 N.A. 44.6 90.1 N.A. 81.5 N.A. 59.5 N.A. 51.8 N.A.
Protein Similarity: 100 99.7 80.6 93.1 N.A. 97.3 96.8 N.A. 51.2 94.6 N.A. 90.7 N.A. 74.2 N.A. 66.1 N.A.
P-Site Identity: 100 90.9 0 81.8 N.A. 72.7 0 N.A. 13.3 0 N.A. 36.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 0 81.8 N.A. 81.8 0 N.A. 33.3 0 N.A. 54.5 N.A. 0 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.3 35.2 N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 54.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 24 0 8 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 31 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 8 39 0 24 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 47 0 0 8 0 8 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 39 0 16 8 0 0 0 0 0 8 8 0 0 8 0 % K
% Leu: 8 8 8 47 0 8 8 16 0 8 0 0 0 8 8 % L
% Met: 0 0 24 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 16 0 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 24 0 8 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 31 0 16 24 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 47 47 47 47 % _