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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT75
All Species:
18.18
Human Site:
T191
Identified Species:
50
UniProt:
O95678
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95678
NP_004684.2
551
59560
T191
L
Q
E
Q
G
S
R
T
V
R
Q
N
L
E
P
Chimpanzee
Pan troglodytes
A5A6M8
592
62520
T212
L
Q
E
Q
G
T
K
T
V
R
Q
N
L
E
P
Rhesus Macaque
Macaca mulatta
XP_001098580
551
59442
T191
L
Q
E
Q
G
S
R
T
V
R
Q
N
L
E
P
Dog
Lupus familis
XP_543650
975
107396
T191
L
Q
E
Q
G
S
K
T
V
R
Q
N
L
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ7
551
59722
T192
L
Q
E
Q
G
S
R
T
V
R
Q
N
L
E
P
Rat
Rattus norvegicus
Q6IG05
542
59008
P189
T
V
R
Q
N
L
E
P
F
F
D
A
Y
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521409
487
53265
D165
N
K
F
A
S
F
I
D
K
V
R
F
L
E
Q
Chicken
Gallus gallus
O93532
492
53785
L170
F
E
A
Y
I
T
N
L
R
R
Q
L
D
G
L
Frog
Xenopus laevis
P16878
513
55433
L189
I
A
N
L
R
R
Q
L
E
S
L
T
N
D
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
96.5
47.6
N.A.
84.9
83.4
N.A.
70.4
63.3
62.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
81.9
98.3
51.3
N.A.
91.8
90.3
N.A.
78.4
75.8
73.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
100
93.3
N.A.
100
6.6
N.A.
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
26.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
12
0
12
12
0
% D
% Glu:
0
12
56
0
0
0
12
0
12
0
0
0
0
67
0
% E
% Phe:
12
0
12
0
0
12
0
0
12
12
0
12
0
0
0
% F
% Gly:
0
0
0
0
56
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
23
0
12
0
0
0
0
0
12
% K
% Leu:
56
0
0
12
0
12
0
23
0
0
12
12
67
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
12
0
12
0
12
0
0
0
0
56
12
0
12
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
56
% P
% Gln:
0
56
0
67
0
0
12
0
0
0
67
0
0
0
12
% Q
% Arg:
0
0
12
0
12
12
34
0
12
67
12
0
0
0
0
% R
% Ser:
0
0
0
0
12
45
0
0
0
12
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
23
0
56
0
0
0
12
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
56
12
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _