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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT75 All Species: 13.94
Human Site: T524 Identified Species: 38.33
UniProt: O95678 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95678 NP_004684.2 551 59560 T524 G G S G F S A T S N R G L G G
Chimpanzee Pan troglodytes A5A6M8 592 62520 G545 S S G G V G L G G G L S V G G
Rhesus Macaque Macaca mulatta XP_001098580 551 59442 T524 G G S G F S A T S N R G L G G
Dog Lupus familis XP_543650 975 107396 G524 R C S R A S S G G A G Y G L G
Cat Felis silvestris
Mouse Mus musculus Q8BGZ7 551 59722 T525 G G S G F T T T S S R G P V G
Rat Rattus norvegicus Q6IG05 542 59008 S515 G G S G F T T S S S R G P V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521409 487 53265 R461 L L E G E E C R L S G E G V S
Chicken Gallus gallus O93532 492 53785 G466 L G A G M G S G A L G F S S G
Frog Xenopus laevis P16878 513 55433 S485 G A G G F G N S S A R F G S G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.4 96.5 47.6 N.A. 84.9 83.4 N.A. 70.4 63.3 62.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81.9 98.3 51.3 N.A. 91.8 90.3 N.A. 78.4 75.8 73.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 20 N.A. 66.6 60 N.A. 6.6 20 40 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 26.6 N.A. 80 80 N.A. 13.3 40 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 12 0 23 0 12 23 0 0 0 0 0 % A
% Cys: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 0 12 12 0 0 0 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 56 0 0 0 0 0 0 23 0 0 0 % F
% Gly: 56 56 23 89 0 34 0 34 23 12 34 45 34 34 89 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 23 12 0 0 0 0 12 0 12 12 12 0 23 12 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 23 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 12 0 0 0 12 0 0 56 0 0 0 0 % R
% Ser: 12 12 56 0 0 34 23 23 56 34 0 12 12 23 12 % S
% Thr: 0 0 0 0 0 23 23 34 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 0 0 0 0 0 12 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _