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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP All Species: 24.55
Human Site: S202 Identified Species: 45
UniProt: O95684 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95684 NP_008976.1 399 43065 S202 A N D E A N Q S D T S V S L S
Chimpanzee Pan troglodytes XP_527596 399 43086 S202 A N D E A N Q S D T S V S L S
Rhesus Macaque Macaca mulatta XP_001102430 399 42988 S202 A N N E A N Q S D T S V S L S
Dog Lupus familis XP_855273 374 40330 S178 A S N D A S Q S D T S I S S A
Cat Felis silvestris
Mouse Mus musculus Q66JX5 399 42740 S202 T S S E T S Q S E P S V S L S
Rat Rattus norvegicus Q4V7C1 399 42993 S202 T S S E T S Q S E P S V S L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509359 156 16754
Chicken Gallus gallus Q5ZJ24 175 19811
Frog Xenopus laevis NP_001089813 440 50470 S244 D I P D I I H S P R R S L E A
Zebra Danio Brachydanio rerio NP_001002125 511 56229 L244 T S D N S D A L Y S S S K T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396617 469 52538 S250 I D S K G N N S M N F D T L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311121 263 29325 S71 R A K Q L H A S P S G R L L T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567013 257 29167 R66 G S C N D R A R Q L H A S P S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.2 81.4 N.A. 84.7 86.9 N.A. 27.5 23.3 42 41.6 N.A. N.A. 28.1 N.A. N.A.
Protein Similarity: 100 99 99 86.7 N.A. 90.9 92.7 N.A. 32.8 31.3 57.2 53.4 N.A. N.A. 46.7 N.A. N.A.
P-Site Identity: 100 100 93.3 53.3 N.A. 53.3 53.3 N.A. 0 0 6.6 13.3 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 0 0 20 46.6 N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: 21.5 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 8 0 0 31 0 24 0 0 0 0 8 0 0 16 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 24 16 8 8 0 0 31 0 0 8 0 0 0 % D
% Glu: 0 0 0 39 0 0 0 0 16 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 0 % H
% Ile: 8 8 0 0 8 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 8 0 0 8 0 8 0 0 16 54 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 24 16 16 0 31 8 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 16 16 0 0 0 8 8 % P
% Gln: 0 0 0 8 0 0 47 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 8 0 8 0 8 8 8 0 0 0 % R
% Ser: 0 39 24 0 8 24 0 70 0 16 54 16 54 8 47 % S
% Thr: 24 0 0 0 16 0 0 0 0 31 0 0 8 8 16 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _