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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP All Species: 22.73
Human Site: S216 Identified Species: 41.67
UniProt: O95684 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95684 NP_008976.1 399 43065 S216 S E P K S K S S L H L L S H E
Chimpanzee Pan troglodytes XP_527596 399 43086 S216 S E P K S K S S L H L L S H E
Rhesus Macaque Macaca mulatta XP_001102430 399 42988 S216 S E S K S K S S L H L L S H E
Dog Lupus familis XP_855273 374 40330 S192 A E P K S K S S L H L L A H E
Cat Felis silvestris
Mouse Mus musculus Q66JX5 399 42740 S216 S E S K S K S S L H S L A H E
Rat Rattus norvegicus Q4V7C1 399 42993 S216 S E S K S K S S L H S L V H E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509359 156 16754
Chicken Gallus gallus Q5ZJ24 175 19811
Frog Xenopus laevis NP_001089813 440 50470 N258 A K A S S Q V N N N Q Q T D D
Zebra Danio Brachydanio rerio NP_001002125 511 56229 S258 T E D K I I L S S A S K A G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396617 469 52538 M264 P T S P N G T M I N H T T K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311121 263 29325 L85 T A L I C E Y L D W G Q L N H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567013 257 29167 L80 S G R L L S A L I C E Y L D W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.2 81.4 N.A. 84.7 86.9 N.A. 27.5 23.3 42 41.6 N.A. N.A. 28.1 N.A. N.A.
Protein Similarity: 100 99 99 86.7 N.A. 90.9 92.7 N.A. 32.8 31.3 57.2 53.4 N.A. N.A. 46.7 N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 80 80 N.A. 0 0 6.6 20 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 80 N.A. 0 0 53.3 40 N.A. N.A. 40 N.A. N.A.
Percent
Protein Identity: 21.5 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 8 0 0 0 8 0 0 8 0 0 24 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 0 0 0 0 16 16 % D
% Glu: 0 54 0 0 0 8 0 0 0 0 8 0 0 0 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 0 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 47 8 0 0 47 8 % H
% Ile: 0 0 0 8 8 8 0 0 16 0 0 0 0 0 0 % I
% Lys: 0 8 0 54 0 47 0 0 0 0 0 8 0 8 0 % K
% Leu: 0 0 8 8 8 0 8 16 47 0 31 47 16 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 8 8 16 0 0 0 8 0 % N
% Pro: 8 0 24 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 16 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 47 0 31 8 54 8 47 54 8 0 24 0 24 0 0 % S
% Thr: 16 8 0 0 0 0 8 0 0 0 0 8 16 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _