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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1OP
All Species:
13.64
Human Site:
S221
Identified Species:
25
UniProt:
O95684
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95684
NP_008976.1
399
43065
S221
K
S
S
L
H
L
L
S
H
E
T
K
I
G
S
Chimpanzee
Pan troglodytes
XP_527596
399
43086
S221
K
S
S
L
H
L
L
S
H
E
T
K
I
G
S
Rhesus Macaque
Macaca mulatta
XP_001102430
399
42988
S221
K
S
S
L
H
L
L
S
H
E
T
K
I
G
S
Dog
Lupus familis
XP_855273
374
40330
A197
K
S
S
L
H
L
L
A
H
E
T
K
I
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q66JX5
399
42740
A221
K
S
S
L
H
S
L
A
H
E
T
R
I
A
S
Rat
Rattus norvegicus
Q4V7C1
399
42993
V221
K
S
S
L
H
S
L
V
H
E
T
R
I
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509359
156
16754
Chicken
Gallus gallus
Q5ZJ24
175
19811
Frog
Xenopus laevis
NP_001089813
440
50470
T263
Q
V
N
N
N
Q
Q
T
D
D
H
I
E
K
N
Zebra Danio
Brachydanio rerio
NP_001002125
511
56229
A263
I
L
S
S
A
S
K
A
G
D
R
R
P
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396617
469
52538
T269
G
T
M
I
N
H
T
T
K
E
T
E
I
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311121
263
29325
L90
E
Y
L
D
W
G
Q
L
N
H
T
L
K
V
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567013
257
29167
L85
S
A
L
I
C
E
Y
L
D
W
A
Q
L
N
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.2
81.4
N.A.
84.7
86.9
N.A.
27.5
23.3
42
41.6
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
100
99
99
86.7
N.A.
90.9
92.7
N.A.
32.8
31.3
57.2
53.4
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
0
0
0
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
0
0
40
33.3
N.A.
N.A.
60
N.A.
N.A.
Percent
Protein Identity:
21.5
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
36.8
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
24
0
0
8
0
0
16
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
16
16
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
54
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
8
0
0
0
0
39
0
% G
% His:
0
0
0
0
47
8
0
0
47
8
8
0
0
0
8
% H
% Ile:
8
0
0
16
0
0
0
0
0
0
0
8
54
0
0
% I
% Lys:
47
0
0
0
0
0
8
0
8
0
0
31
8
8
0
% K
% Leu:
0
8
16
47
0
31
47
16
0
0
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
16
0
0
0
8
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
8
16
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
24
0
0
0
% R
% Ser:
8
47
54
8
0
24
0
24
0
0
0
0
0
0
47
% S
% Thr:
0
8
0
0
0
0
8
16
0
0
62
0
0
0
8
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _