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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR1OP
All Species:
22.12
Human Site:
S254
Identified Species:
40.56
UniProt:
O95684
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95684
NP_008976.1
399
43065
S254
E
D
D
M
E
G
D
S
F
F
D
D
P
I
P
Chimpanzee
Pan troglodytes
XP_527596
399
43086
S254
E
D
D
M
E
G
D
S
F
F
D
D
P
I
P
Rhesus Macaque
Macaca mulatta
XP_001102430
399
42988
S254
E
D
D
M
E
G
D
S
F
F
D
D
P
I
P
Dog
Lupus familis
XP_855273
374
40330
S229
D
G
D
M
E
G
D
S
F
F
D
D
P
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q66JX5
399
42740
S254
G
D
D
V
E
G
D
S
F
F
D
D
P
I
P
Rat
Rattus norvegicus
Q4V7C1
399
42993
S254
E
D
D
V
E
G
D
S
F
F
D
D
P
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509359
156
16754
K12
K
G
H
G
K
Q
K
K
S
G
E
K
S
G
E
Chicken
Gallus gallus
Q5ZJ24
175
19811
E31
I
K
A
R
I
R
A
E
V
F
N
A
L
D
D
Frog
Xenopus laevis
NP_001089813
440
50470
L295
D
T
K
P
D
F
N
L
N
K
I
S
F
D
N
Zebra Danio
Brachydanio rerio
NP_001002125
511
56229
K366
L
S
A
I
G
S
D
K
E
G
D
G
E
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396617
469
52538
L319
N
N
I
N
S
L
E
L
Q
I
V
N
N
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002311121
263
29325
N119
L
K
E
F
S
S
K
N
G
Y
D
L
N
R
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567013
257
29167
R113
D
S
W
K
S
E
I
R
D
F
S
I
N
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.2
81.4
N.A.
84.7
86.9
N.A.
27.5
23.3
42
41.6
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
100
99
99
86.7
N.A.
90.9
92.7
N.A.
32.8
31.3
57.2
53.4
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
0
6.6
0
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
20
13.3
20
20
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
21.5
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
36.8
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
39
47
0
8
0
54
0
8
0
62
47
0
24
8
% D
% Glu:
31
0
8
0
47
8
8
8
8
0
8
0
8
0
8
% E
% Phe:
0
0
0
8
0
8
0
0
47
62
0
0
8
0
0
% F
% Gly:
8
16
0
8
8
47
0
0
8
16
0
8
0
8
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
8
0
8
0
0
8
8
8
0
47
0
% I
% Lys:
8
16
8
8
8
0
16
16
0
8
0
8
0
0
0
% K
% Leu:
16
0
0
0
0
8
0
16
0
0
0
8
8
0
0
% L
% Met:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
8
0
0
8
8
8
0
8
8
24
8
16
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
47
0
47
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
8
0
8
0
0
0
0
0
8
0
% R
% Ser:
0
16
0
0
24
16
0
47
8
0
8
8
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
16
0
0
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _