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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1OP All Species: 22.12
Human Site: S284 Identified Species: 40.56
UniProt: O95684 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95684 NP_008976.1 399 43065 S284 A G S L A S L S D A P P L K S
Chimpanzee Pan troglodytes XP_527596 399 43086 S284 A G S L A L L S D A P P L K S
Rhesus Macaque Macaca mulatta XP_001102430 399 42988 S284 P G S L A S L S D A P P L K S
Dog Lupus familis XP_855273 374 40330 S259 A G S L A S L S D A P P L K S
Cat Felis silvestris
Mouse Mus musculus Q66JX5 399 42740 S284 V G G L A S L S D K P H L R S
Rat Rattus norvegicus Q4V7C1 399 42993 S284 V G G L A S L S D K P H L R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509359 156 16754 L42 E T K S K S S L H I L A N E T
Chicken Gallus gallus Q5ZJ24 175 19811 L61 N E L I R E Y L E F N K Y K Y
Frog Xenopus laevis NP_001089813 440 50470 P325 S F F D D P I P K P E K M Y G
Zebra Danio Brachydanio rerio NP_001002125 511 56229 L396 R E G L G G S L G K A F T S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396617 469 52538 S349 K K S H S I L S N L P P L N G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002311121 263 29325 G149 K F E N L S Q G R G T G R R M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567013 257 29167 F143 V L E G F L K F E N M T Q V M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.2 81.4 N.A. 84.7 86.9 N.A. 27.5 23.3 42 41.6 N.A. N.A. 28.1 N.A. N.A.
Protein Similarity: 100 99 99 86.7 N.A. 90.9 92.7 N.A. 32.8 31.3 57.2 53.4 N.A. N.A. 46.7 N.A. N.A.
P-Site Identity: 100 93.3 93.3 100 N.A. 66.6 66.6 N.A. 6.6 6.6 0 6.6 N.A. N.A. 40 N.A. N.A.
P-Site Similarity: 100 93.3 93.3 100 N.A. 73.3 73.3 N.A. 20 20 20 6.6 N.A. N.A. 53.3 N.A. N.A.
Percent
Protein Identity: 21.5 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 0 0 47 0 0 0 0 31 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 0 0 47 0 0 0 0 0 0 % D
% Glu: 8 16 16 0 0 8 0 0 16 0 8 0 0 8 0 % E
% Phe: 0 16 8 0 8 0 0 8 0 8 0 8 0 0 0 % F
% Gly: 0 47 24 8 8 8 0 8 8 8 0 8 0 0 24 % G
% His: 0 0 0 8 0 0 0 0 8 0 0 16 0 0 0 % H
% Ile: 0 0 0 8 0 8 8 0 0 8 0 0 0 0 0 % I
% Lys: 16 8 8 0 8 0 8 0 8 24 0 16 0 39 0 % K
% Leu: 0 8 8 54 8 16 54 24 0 8 8 0 54 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 16 % M
% Asn: 8 0 0 8 0 0 0 0 8 8 8 0 8 8 0 % N
% Pro: 8 0 0 0 0 8 0 8 0 8 54 39 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 0 8 0 0 0 8 0 0 0 8 24 0 % R
% Ser: 8 0 39 8 8 54 16 54 0 0 0 0 0 8 47 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 8 8 8 0 8 % T
% Val: 24 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 8 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _